Can Common Pain Relievers Fight "Superbugs"?
the MPR take:
Common non-steroidal anti-inflammatory drugs (NSAIDs) may help to prevent the rise of antibiotic-resistant bacteria ("superbugs") by providing an alternative treatment for infections, according to research published in the journal Chemistry and Biology. Unlike existing antibiotics, NSAIDs work by binding to the protein DNA Clamp that is required for bacterial replication. Conventionally, bacterial infections have been treated with antibiotics which work by inhibiting bacterial reproduction or by breaking down the cell walls of bacteria. The NSAIDs used in the study included bromfenac, carprofen, and vedaprofen. More studies will need to be conducted to see if commonly used NSAIDs such as ibuprofen and naproxen have similar effects. Given that antibiotic resistance continues to be a serious healthcare issue, the development of an alternative to traditional antibiotics is a promising step towards helping to solve this problem.
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