Baxdela Yields High Response Against Fluoroquinolone-Non-Susceptible MRSA

Treatment with Baxdela resulted in high response rates against fluoroquinolone-resistant bugs, such as MRSA
Treatment with Baxdela resulted in high response rates against fluoroquinolone-resistant bugs, such as MRSA

Melinta Therapeutics announced new data regarding Baxdela (delafloxacin) activity against fluorquinolone-susceptible and fluoroquinolone-resistant Staphylococcus aureus isolates. The full findings were published in Antimicrobial Agents and Chemotherapy.

The analysis included study patients from the Phase 3 PROCEED trial. Treatment with Baxdela resulted in high response rates against fluoroquinolone-resistant bugs, eradicating levofloxacin-non-susceptible S. aureus infections in 98.8% of evaluable cases, and levofloxacin-non-susceptible methicillin-resistant S. aureus infections in 98.6% of evaluable cases. 

Related Articles

Baxdela also yielded high response rates against S. aureus isolates with mutations in the Quinolone Resistance Determining Region (QRDR) in 98.8% of cases. QRDR mutations lower the fluoroquinolone binding and increase resistance.

Baxdela, a fluoroquinolone antibiotic, was approved for the treatment of acute bacterial skin & skin structure infections (ABSSSI). It is currently being evaluated in patients with community-acquired bacterial pneumonia (CABP). Baxdela for injection is supplied as a sterile, lyophilized powder in 300mg single-dose vials. The oral tablets are available in a 450mg strength in 20-count bottles. 

For more information call (844) 635-4682 or visit Baxdela.com.