AAAAI: 2000 to 2009 Saw Rise in Angioedema Hospitalizations
(HealthDay News) – The rate of angioedema hospitalization has increased over the last decade, especially among African-Americans, according to a study presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology, held from March 2–6 in Orlando, FL.
Robert Y. Lin, MD, of the New York Downtown Hospital in New York City, and RJ Levine, of New York Medical College in Valhalla, queried a US national hospitalization database for admissions due to angioedema and other allergic disorders to investigate angioedema hospitalization trends from 2000–2009. Clinical and demographic associations with these trends were assessed.
The researchers found that the rate of angioedema hospitalization rose from 2.7/105 in 2000 to 4.2/105 in 2009. During the same period, the hospitalization rate for other allergic disorders was stable at 1.5/105. The proportion of African-Americans increased from 32% of angioedema admissions in 2000 to 41% of admissions in 2009. Adverse drug effects due to cardiovascular/hypertension agents correlated strongly with angioedema, and increased from 22% in 2000 to 36% in 2009. Adverse drug effects were seen in 38% of African-American patients and 25% of patients of other races who were hospitalized for angioedema.
"Angioedema hospitalization rates have continued to rise from 2000–2009 in the United States, especially in the African-American population. Hospitalization rates of angioedema continue to exceed hospitalization rates of other acute allergic reactions," the authors write.