Generic Name and Formulations:
Nepafenac 0.1%, oph. susp; contains benzalkonium chloride.
Company:
Alcon Laboratories, Inc.
Post-operative pain and inflammation following cataract surgery.
≥10yrs: 1 drop in affected eye(s) 3 times daily starting one day before surgery, continued on day of surgery, and through first 2 weeks post-op.
<10yrs: not recommended.
NSAID.
Bleeding tendencies. May delay wound healing. Complicated/repeat ocular surgeries. Corneal defects/denervation. Ocular surface diseases. Rheumatoid arthritis. Diabetes. Monitor cornea; discontinue if corneal epithelial breakdown occurs. Contact lenses (remove during therapy). Risk of corneal adverse events may be increased if used more than 24 hours before surgery, or beyond 14 days post-op. Pregnancy (Cat.C; avoid during 3rd trimester). Nursing mothers.
May potentiate oral anticoagulants, others that prolong bleeding.
Ocular effects (eg, capsular opacity, decreased visual acuity, foreign body sensation, increased intraocular pressure, sticky sensation, edema, dry eye, lid margin crusting, discomfort, hyperemia, pain, pruritus, photophobia, tearing, vitreous detachment), headache, hypertension, GI upset, sinusitis.
Susp—3mL