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Generic Name and Formulations:

Chloroprocaine HCl 10mg/mL, 20mg/mL; soln for inj; contains methylparaben.

Select therapeutic use:

Indications for NESACAINE:

Production of local anesthesia by infiltration and peripheral nerve block.


Epidural anesthesia: administer test dose first; monitor for CNS or cardiovascular toxicity. See literature for dosing based on procedure. Individualize. Max single recommended dose: 11mg/kg, not to exceed max total dose of 800mg. Debilitated, elderly, acutely ill (cardiac and/or liver disease): reduce dose.


<3yrs: see literature. Individualize based on age and weight. ≥3yrs: max 11mg/kg.


Not for subarachnoid administration. Lumbar and caudal epidural anesthesia: caution with existing neurological disease, spinal deformities, septicemia, severe hypertension. To be administered under the supervision of experienced clinicians. Have intubation, artificial respiration, oxygen therapy and reversal agents available. Hypotension. Heart block. Monitor cardiovascular and respiratory vital signs. Hepatic impairment. Retrobulbar block. Labor & delivery. Pregnancy (Cat.C). Nursing mothers.

See Also:


Pharmacological Class:

Local anesthetic.


Concomitant sulfonamides: not recommended.

Adverse Reactions:

CNS effects (eg, excitation, depression, restlessness, anxiety, dizziness, tremors), cardiovascular effects (eg, myocardium depression, decreased cardiac output, heart block, hypotension, bradycardia, ventricular arrhythmias, cardiac arrest), allergic-type reactions, neurologic effects (eg, spinal block, urinary retention, paresthesia, weakness, headache, paralysis of lower extremities).

How Supplied:

Nesacaine: Multi-dose vial (30mL)—1; Nesacaine-MPF: Single-dose vial (20mL)—1