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Narcotic Analgesic Medications

March 09, 2012

Narcotic Analgesics (download)

NARCOTIC ANALGESICS

Active ingredient(s)	Brand	Formulation	Strength(s)	Dose interval*
OPIOID AGONISTS
fentanyl	ABSTRAL	sublingual tabs	100mcg, 200mcg, 300mcg, 400mcg, 600mcg, 800mcg	See entry
	ACTIQ	units for transmucosal administration	200mcg, 400mcg, 600mcg, 800mcg, 1200mcg, 1600mcg	See entry
	DURAGESIC	transdermal system	12mcg/hr, 25mcg/hr, 50mcg/hr, 75mcg/hr, 100mcg/hr	72 hours
	FENTORA	buccal tabs	100mcg, 200mcg, 400mcg, 600mcg, 800mcg	See entry
	LAZANDA	nasal spray	100mcg, 400mcg per 100mcL	2 hours (see entry)
	ONSOLIS	buccal soluble film	200mcg, 400mcg, 600mcg, 800mcg, 1200mcg	See entry
hydromorphone	DILAUDID	tabs	2mg, 4mg, 8mg	4–6 hours
		liq	5mg per 5mL	3–6 hours
		rectal supps	3mg	6–8 hours
		inj (SC, IM, or IV)	1mg, 2mg, 4mg per mL	4–6 hours
	DILAUDID-HP	inj (SC, IM, or IV)	10mg per mL	4–6 hours
	EXALGO	ext-rel tabs	8mg, 12mg, 16mg	24 hours
meperidine	DEMEROL	tabs	50mg, 100mg	3–4 hours
meperidine	DEMEROL	syrup	50mg per 5mL	3–4 hours
morphine sulfate	AVINZA	ext-rel caps	30mg, 45mg, 60mg, 75mg, 90mg, 120mg	24 hours
	DEPODUR	ext-rel susp for inj	10mg/mL	—
	KADIAN	sust-rel pellets in caps	10mg, 20mg, 30mg, 50mg, 60mg, 80mg, 100mg, 200mg	12–24 hours
	MS CONTIN	sust-rel tabs	15mg, 30mg, 60mg, 100mg, 200mg	12 hours
	MORPHINE SULFATE	scored tabs	15mg, 30mg	4 hours
	MORPHINE SULFATE	oral soln	10mg, 20mg, 100mg¹ per 5mL	4 hours
	ORAMORPH SR	sust-rel tabs	15mg, 30mg, 60mg, 100mg	12 hours
oxycodone	OXECTA	tabs	5mg, 7.5mg	4–6 hours
	OXYCONTIN	controlled-rel tabs	10mg, 15mg, 20mg, 30mg, 40mg, 60mg, 80mg	12 hours
	OXYIR	caps	5mg	6 hours
oxymorphone HCl	OPANA	tabs	5mg, 10mg	4–6 hours
oxymorphone HCl	OPANA ER	ext-rel tabs	5mg, 10mg, 20mg, 30mg, 40mg	12 hours
tapentadol HCl	NUCYNTA	tabs	50mg, 75mg, 100mg	4–6 hours
tapentadol HCl	NUCYNTA ER	ext-rel tabs	50mg, 100mg, 150mg, 200mg, 250mg	12 hours
OPIOID AGONISTS + NON-OPIOIDS
codeine + APAP	TYLENOL w. CODEINE #3	tabs	30mg + 300mg	4 hours
codeine + APAP	TYLENOL w. CODEINE #4	tabs	60mg + 300mg	4 hours
dihydrocodeine + ASA + caffeine	SYNALGOS-DC	caps	16mg + 356.4mg + 30mg	4 hours
hydrocodone + APAP	LORTAB 2.5/500	scored tabs	2.5mg + 500mg	4–6 hours
	LORTAB 5/500	scored tabs	5mg + 500mg
	LORTAB 7.5/500	scored tabs	7.5mg + 500mg
	LORTAB 10/500	scored tabs	10mg + 500mg
	LORTAB ELIXIR	liq	7.5mg + 500mg per 15mL
	MAXIDONE	scored tabs	10mg + 750mg	4–6 hours
	NORCO 5/325	scored tabs	5mg + 325mg	4–6 hours
	NORCO 7.5/325	scored tabs	7.5mg + 325mg
	NORCO 10/325	scored tabs	10mg + 325mg
	VICODIN	scored tabs	5mg + 500mg	4–6 hours
	VICODIN ES	scored tabs	7.5mg + 750mg
	VICODIN HP	scored tabs	10mg + 660mg
	XODOL 5/300	scored tabs	5mg + 300mg	4–6 hours
	XODOL 7.5/300	scored tabs	7.5mg + 300mg
	XODOL 10/300	scored tabs	10mg + 300mg
	ZYDONE 5/400	tabs	5mg + 400mg	4–6 hours
	ZYDONE 7.5/400	tabs	7.5mg + 400mg
	ZYDONE 10/400	tabs	10mg + 400mg
hydrocodone + ibuprofen	IBUDONE	tabs	5mg + 200mg; 10mg + 200mg	4–6 hours
hydrocodone + ibuprofen	VICOPROFEN	tabs	7.5mg + 200mg	4–6 hours
oxycodone (HCl) + APAP	MAGNACET	tabs	2.5mg + 400mg, 5mg + 400mg, 7.5mg + 400mg, 10mg + 400mg	6 hours
	PERCOCET 2.5/325	tabs	2.5mg + 325mg	6 hours
	PERCOCET 5/325	scored tabs	5mg + 325mg
	PERCOCET 7.5/325	tabs	7.5mg + 325mg
	PERCOCET 7.5/500	tabs	7.5mg + 500mg
	PERCOCET 10/325	tabs	10mg + 325mg
	PERCOCET 10/650	tabs	10mg + 650mg
	ROXICET	oral soln	5mg + 325mg	6 hours
	TYLOX	caps	5mg + 500mg	6 hours
oxycodone (HCl) + ASA	PERCODAN	scored tabs	4.8355mg + 325mg	6 hours
oxycodone + ibuprofen	COMBUNOX	scored tabs	5mg + 400mg	6 hours
OPIOID AGONIST + OPIOID ANTAGONISTS
morphine sulfate + naltrexone	EMBEDA	ext-rel caps	20mg/0.8mg, 30mg/1.2mg, 50mg/2mg, 60mg/2.4mg, 80mg/3.2mg, 100mg/4mg	12–24 hours
OPIOID AGONIST/ANTAGONISTS
buprenorphine	BUTRANS	transdermal system	5mcg/hr, 10mcg/hr, 20mcg/hr	7 days
butorphanol	BUTORPHANOL NS	nasal spray	1mg, per spray	3–4 hours
nalbuphine	—	inj (IV, IM, or SC)	10mg, 20mg per mL	3–6 hours
OPIOID AGONIST/ANTAGONISTS + NON-OPIOIDS
pentazocine + naloxone	TALWIN-NX	scored tabs	50mg + 0.5mg	3–4 hours
NOTES
*Usual dosing interval is listed. Doses must be individualized. APAP = acetaminophen; ASA = aspirin; ¹ = opioid-tolerant only Not an inclusive list. (Rev. 3/2012)

Nonmedical Prescription Pain Medication Use Peaks at Age 16

May 10, 2012

Use of prescription pain relievers to get high or for other nonmedical purposes (extramedical use) peaks around age 16 years.

PAS: Maternal Opioid Use, Neonatal Withdrawal Rising

May 01, 2012

From 2000-2009, there was a significant increase in the incidence of maternal opioid use and in the diagnosis of neonatal abstinence syndrome (NAS).

Hyperalgesia Similar With Drug Therapies for Heroin Addiction

April 26, 2012

Heroin-addicted patients treated with methadone or buprenorphine have a heightened sensitivity to pain, and the hyperalgesia does not change over the course of treatment.

Patients With Acute Low Back Pain Have Poor Prognosis

April 24, 2012

Few patients with acute low back pain (LBP), with or without sciatica, declare sick leave; however, approximately half have one or more recurrences and a considerable proportion experience chronic pain six months or longer after the initial episode.

Alcohol Use With Opioids Common Even Without Abuse Past

April 16, 2012

Alcohol or sedative use during chronic opioid therapy (COT) for non-cancer pain puts patients at risk for adverse events such as respiratory depression or sedation, and the risk of concurrent use of central nervous system (CNS) depressants is not limited to patients with a history of substance abuse.

KADIAN

Pain & Pyrexia > Narcotic analgesics

Morphine sulfate 10mg, 20mg, 30mg, 50mg, 60mg, 80mg, 100mg, 200mg; sust-rel pellets in caps.

Updated: 4/8/2009

LORCET PLUS

Pain & Pyrexia > Narcotic analgesics

Hydrocodone bitartrate 7.5mg, acetaminophen 650mg; scored tabs.

Morphine sulfate oral solution

Pain & Pyrexia > Narcotic analgesics

Morphine sulfate 10mg/5mL, 20mg/5mL, 100mg/5mL.

Updated: 5/2/2011

NORCO 10/325

Pain & Pyrexia > Narcotic analgesics

Hydrocodone bitartrate 10mg, acetaminophen 325mg; scored tabs.

PERCOCET 5/325

Pain & Pyrexia > Narcotic analgesics

Oxycodone HCl 5mg, acetaminophen 325mg; scored tabs.

ASTELIN

Respiratory Tract > Rhinitis/rhinorrhea (intranasal products)

Adverse reactions updated.

Updated: 5/8/2012

ATRAPRO ANTIPRURITIC HYDROGEL

Dermatological Disorders > Pruritus and dry skin

Monograph added.

Updated: 4/25/2012

ATRAPRO DERMAL SPRAY

Dermatological Disorders > Pressure/neuropathic ulcers

Monograph added.

Updated: 4/24/2012

B-NEXA

Nutrition > Vitamins/minerals/supplements

Monograph added.

Updated: 4/30/2012

BYDUREON

Endocrine System > Diabetes

Monograph added.

Updated: 4/20/2012

Pain & Pyrexia > Narcotic analgesics

Narcotic analgesics exert their effects by binding to mu, kappa, and delta-type opioid receptors. These receptor subtypes differ in their ...
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Schedules of Controlled Substances categorized by the FDA.

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