NALFON Rx

Select the drug indication to add to your list

NALFON

Arthritis/rheumatic disorders
Nonnarcotic analgesics
Only 4 drugs may be compared at once

Generic Name and Formulations:

Fenoprofen calcium 200mg, 400mg; caps.

Select therapeutic use:

Indications for NALFON:

Rheumatoid arthritis. Osteoarthritis.

Adult:

Use lowest effective dose for shortest duration. 400mg–600mg 3 or 4 times daily. Max: 3.2g/day.

Children:

<18yrs: not established.

Contraindications:

Aspirin allergy. Coronary artery bypass graft surgery.

Warnings/Precautions:

Increased risk of serious cardiovascular events (including MI, stroke). Avoid in recent MI, severe heart failure; if necessary, monitor. Increased risk of serious GI adverse events (including inflammation, bleeding, ulceration, perforation). History of ulcer disease and/or GI bleeding. Hypertension; monitor BP closely. Hepatic or renal impairment. Discontinue if signs/symptoms of liver disease develop, or if abnormal LFTs persist or worsen. Dehydration. Hypovolemia. Advanced renal disease: not recommended. Hyperkalemia. Coagulation disorders. Monitor CBCs, blood chemistry, hepatic, renal, and ocular function in long-term therapy. Pre-existing asthma. May mask signs of infection or fever. Discontinue at 1st sign of rash or any other hypersensitivity. Hearing impaired. Elderly. Debilitated. Labor & delivery. Pregnancy (3rd trimester; avoid). Nursing mothers.

Interactions:

Avoid concomitant aspirin, salicylates (eg, diflunisal, salsalate) or other NSAIDs. Increased risk of GI bleed with anticoagulants (monitor), antiplatelets, oral corticosteroids, SSRIs, SNRIs, smoking, alcohol, or prolonged NSAID therapy. May antagonize, or increase risk of renal failure with diuretics (eg, loop or thiazides), ACE inhibitors (eg, captopril), ARBs (eg, losartan), or β-blockers; monitor closely. Potentiates digoxin; monitor levels. May potentiate lithium, methotrexate, cyclosporine; monitor for toxicity. Concomitant with pemetrexed may increase risk of pemetrexed-associated myelosuppression, renal, and GI toxicity. May be antagonized by phenobarbital. May potentiate protein-bound drugs (eg, hydantoins, sulfonamides, sulfonylureas).

Pharmacological Class:

NSAID (arylacetic acid deriv.).

Adverse Reactions:

Dyspepsia, headache, somnolence, nausea, dizziness, constipation, nervousness, asthenia, peripheral edema; cardiovascular thrombotic events, GI ulcer/bleed, hepatotoxicity, renal toxicity, hypertension, serious skin reactions, anemia/blood dyscrasias.

How Supplied:

Caps 200mg—100; 400mg—90, 500

NALFON 400mg capsules (Qty:90)

appx. price $420.00

Indications for NALFON:

Mild to moderate pain.

Adult:

Use lowest effective dose for shortest duration. 200mg every 4–6hrs as needed.

Children:

<18yrs: not established.

Contraindications:

Aspirin allergy. Coronary artery bypass graft surgery.

Warnings/Precautions:

Increased risk of serious cardiovascular events (including MI, stroke). Avoid in recent MI, severe heart failure; if necessary, monitor. Increased risk of serious GI adverse events (including inflammation, bleeding, ulceration, perforation). History of ulcer disease and/or GI bleeding. Hypertension; monitor BP closely. Hepatic or renal impairment. Discontinue if signs/symptoms of liver disease develop, or if abnormal LFTs persist or worsen. Dehydration. Hypovolemia. Advanced renal disease: not recommended. Hyperkalemia. Coagulation disorders. Monitor CBCs, blood chemistry, hepatic, renal, and ocular function in long-term therapy. Pre-existing asthma. May mask signs of infection or fever. Discontinue at 1st sign of rash or any other hypersensitivity. Hearing impaired. Elderly. Debilitated. Labor & delivery. Pregnancy (3rd trimester; avoid). Nursing mothers.

Interactions:

Avoid concomitant aspirin, salicylates (eg, diflunisal, salsalate) or other NSAIDs. Increased risk of GI bleed with anticoagulants (monitor), antiplatelets, oral corticosteroids, SSRIs, SNRIs, smoking, alcohol, or prolonged NSAID therapy. May antagonize, or increase risk of renal failure with diuretics (eg, loop or thiazides), ACE inhibitors (eg, captopril), ARBs (eg, losartan), or β-blockers; monitor closely. Potentiates digoxin; monitor levels. May potentiate lithium, methotrexate, cyclosporine; monitor for toxicity. Concomitant with pemetrexed may increase risk of pemetrexed-associated myelosuppression, renal, and GI toxicity. May be antagonized by phenobarbital. May potentiate protein-bound drugs (eg, hydantoins, sulfonamides, sulfonylureas).

Pharmacological Class:

NSAID (arylacetic acid deriv.).

Adverse Reactions:

Dyspepsia, headache, somnolence, nausea, dizziness, constipation, nervousness, asthenia, peripheral edema; cardiovascular thrombotic events, GI ulcer/bleed, hepatotoxicity, renal toxicity, hypertension, serious skin reactions, anemia/blood dyscrasias.

How Supplied:

Caps 200mg—100; 400mg—90, 500

NALFON 400mg capsules (Qty:90)

appx. price $420.00