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Muscle spasms
Only 4 drugs may be compared at once

Generic Name and Formulations:

Rimabotulinumtoxin B 2500 Units/0.5mL, 5000 Units/1mL, 10000 Units/2mL; soln for IM inj; contains human albumin; preservative-free.

Select therapeutic use:

Indications for MYOBLOC:

Cervical dystonia, to reduce severity of abnormal head position and neck pain.


Should be administered and managed by experienced physicians. Individualize. Treatment-experienced: Initially 2500 to 5000 Units divided among affected muscles. Treatment-naïve: use lower initial dose. Adjust subsequent doses based on response.


Not recommended.


Infection at proposed inj site.

Boxed Warning:

Distant spread of toxin effect.


Not interchangeable with other botulinum toxin products. Spread of botulinum toxin effects my be observed beyond the local injection site. Pre-existing dysphagia. Respiratory disorders. Neuromuscular disorders (eg, myasthenia gravis, ALS, Lambert-Eaton syndrome); monitor closely. Contains human albumin; monitor for possible viral disease transmission. Pregnancy (Cat.C). Nursing mothers.

Pharmacological Class:

Neuromuscular blocker.


May be potentiated by aminoglycosides or other agents interfering with neuromuscular transmission (eg, curare-like compounds). Concomitant other botulinum toxin products may potentiate neuromuscular paralysis.

Adverse Reactions:

Inj site reactions, dry mouth, dysphagia (may be severe), dyspepsia, headache; respiratory difficulties, allergic reactions (discontinue if occurs).

Generic Availability:


How Supplied:

Single-use vial—1