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Short-term therapy with vitamin C at modest doses did not have a clinically significant effect on lowering urate levels in patients with gout.
Increased loading of the lumbar spine, arising from lifestyle activities, could contribute to the degenerative process and lead to development of degenerative lumbar spinal stenosis.
The presence of retrolisthesis in patients undergoing decompressive surgery for a lumbar disc herniation may result in significantly worse lower back pain and physical function over four years.
Combination therapy with teriparatide and denosumab may be most effective in treating postmenopausal women with osteoporosis at risk for fracture.