Iroko announced that the Food and Drug Administration (FDA) has approved Zorvolex (diclofenac) capsules for the management of osteoarthritis pain.
Eagle Pharmaceuticals announced that the FDA has approved Ryanodex (dantrolene sodium) for injectable suspension, an antidote for the management of malignant hyperthermia (MH), along with the appropriate supportive measures.
American Health Packaging announced a voluntary recall of Ibuprofen Tablets 600mg and Oxcarbazepine Tables 300mg due to mislabeled inner unit dose blister packaging.
Medac Pharma announced that the FDA has approved Rasuvo (methotrexate) subcutaneous auto-injector for the management of rheumatoid arthritis, polyarticular-course juvenile idiopathic arthritis (pJIA), and severe, recalcitrant, disabling psoriasis.
EarlySense has announced that the FDA has issued clearance for the Chair Sensor Solution, the first automatic contact-free sensor for continuous monitoring of patients' vital signs in a chair.
The FDA has cleared the first motorized device intended to act as an exoskeleton in individuals with paraplegia due to spinal cord injuries for use at home and in the community.
At EULAR 2014, scientists presented the possibility of using biomarkers to predict disease outcomes at 12 months in children with juvenile idiopathic arthritis (JIA).
Increased healthcare costs were associated with musculoskeletal disorders compared to other disease states, according to a new study presented at EULAR 2014.
Positions 11, 71, and 74 of the HLA-DRB1 gene was shown to be strong independent genetic determinants of radiological damage in rheumatoid arthritis (RA).
A potential biomarker of response to anti-TNF therapies in patients with rheumatoid arthritis (RA) has been identified, which could lead to the personalization of RA treatment.
Erectile dysfunction (ED) is present and frequently severe in most men with gout, reports research presented at the European League Against Rheumatism Annual Congress (EULAR 2014).
Cranial ultrasound is superior in sensitivity and has comparable specificity in the diagnosis of giant cell arteritis (GCA) compared to temporal artery biopsy (TAB), according to a new study.
At EULAR 2014, two studies shed insight on the relationship between dietary intake of monounsaturated fatty acids and cholesterol with disease activity in rheumatoid arthritis (RA) and osteoarthritis (OA), respectively.
CT-P13, an infliximab biosimilar, achieved statistically similar improvements in disease activity disability, and mobility in patients with ankylosing spondylitis (AS) compared to infliximab, results from the PLANETAS study found at EULAR 2014.
Romosozumab was found to significantly increase bone mineral density and bone content in the spine and hip in postmenopausal women compared to baseline and also compared to teriparatide and placebo, as presented at EULAR 2014.
Many patients with psoriatic arthritis were not receiving doses of TNFα inhibitor, adalimumab, to obtain optimal clinical benefit, according to data presented at EULAR 2014.
At EULAR 2014, new research showed that ultrasound-guided injections of growth factors-containing platelet-rich plasma (PRP) are no more effective than saline injection sin treating recently developed epicondylitis.
Obese patients with rheumatoid arthritis (RA) have higher disease activity scores (DAS) than non-obese patients, regardless of their disease stage, scientists presented at EULAR 2014.
Recent findings identify a correlation between the presence of biomarkers in the blood (micro RNAs [miRNAs]) and the development of severe osteoarthritis of the knee or hip joint, as presented at EULAR 2014.
New research showed that it is possible to successfully stop immunosuppressant therapy without triggering a flare for the majority of lupus patients in remission, as presented at EULAR 2014.
Auxilium Pharmaceuticals announced new data from its Phase 3 IMPRESS trials that evaluated Xiaflex for the treatment of Peyronie's disease at the 2014 Annual Meeting of the AUA.
DEKA Integrated Solutions has received FDA marketing approval for the DEKA Arm System, the first prosthetic arm that can perform multiple, simultaneous powered movements controlled by electrical signals from electromyogram (EMG) electrode in individuals with upper extremity amputations occurring at the shoulder joint, mid-upper arm, or mid-lower arm.
Nano Well-Being Health is issuing a voluntary recall of two lots of Super Arthgold 500mg capsules, a dietary supplement for joint pain and arthritis.
The FDA is warning patients and healthcare professionals about the potential for rare but serious adverse events associated with injection of corticosteroids into the epidural space of the spine.
Sarepta Therapeutics has announced its plans to submit a New Drug Application (NDA) for eteplirsen for the treatment of Duchenne muscular dystrophy (DMD).
Antares Pharma announced the publication of results from its crossover study comparing the relative bioavailability, safety, and tolerability of Otrexup (methotrexate) to oral methotrexate (MTX) in adults with rheumatoid arthritis in the Annals of the Rheumatic Diseases.
ReCept announced that it is one of the specialty pharmacies selected to distribute Otezla (apremilast; Celgene), a recently approved drug for adults with active psoriatic arthritis.
Ampio announced results of the 20 weeks extension of the SPRING study of Ampion for the treatment of osteoarthritis of the knee (OAK).
A novel therapy that involves electrical stimulation of the spinal cord has resulted in four individuals with paraplegia now being able to voluntarily move previously paralyzed muscles
The FDA has approved Otezla (apremilast; Celgene) tablets for the treatment of adults with active psoriatic arthritis.
Among U.S. patients undergoing spinal fusion, the rates of allogeneic blood transfusion increased from 2000-2009, while predonated autologous blood transfusion rates decreased.
Eagle Pharmaceuticals announced that the FDA has accepted the NDA for Ryanodex (dantrolene sodium) and has granted a priority review classification for the treatment of malignant hyperthermia.
Same-day bilateral total knee arthroplasty (BTKA) is safe in rheumatoid arthritis (RA) patients.
Neuromuscular training of all young athletes is a cost-effective strategy for reducing the costs and morbidity associated with ACL injuries.
The incidence of head and neck injuries (HNIs) resulting from participation in extreme sports increased from 2000-2011.
For patients undergoing primary total knee replacement, surgical, radiographic, and demographic variables associated with postoperative pain have been identified in two studies.
There is a substantially high rate of repeat spine imaging when patients with known spinal injuries are transferred from an outside hospital to a tertiary receiving institution.
Multiple 60-minute massage sessions are effective for neck dysfunction and pain among patients with chronic neck pain.
Oral glucosamine supplementation is not associated with a decrease in knee cartilage deterioration among individuals with chronic knee pain.
Pain Free By Nature announced a recall of Reumofan Plus Tablets because they were found to contain the following undeclared active ingredients: methocarbamol and diclofenac.
An estimated 4.5 million people are living with an artificial hip, and 6.7 million people in the United States are currently living with an artificial knee.
Receipt of a primary elective knee or hip total joint arthroplasty (TJA) for osteoarthritis (OA) provides a cardiovascular protective benefit.
Nonagenarian patients can safely undergo a total hip arthroplasty (THA), according to a recent study.
Patients undergoing lumbar spine surgery at teaching hospitals incur longer hospitalizations and have more postoperative complications compared to those treated at nonteaching hospitals.
Purdue Pharma announced results from a Phase 3 study of an extended-release formulation of hydrocodone bitartrate in patients with chronic low back pain.
Scientists can predict who will respond to NSAID treatment by assessing the nervous system's own capacity to regulate pain
For patients with spinal stenosis without degenerative spondylolisthesis, predominance of back pain versus leg pain is associated with worse surgical outcomes
Health care professionals should currently discourage rheumatology patients from using herbal cannabis as a therapy.
In patients with statin-related myalgia, single-patient randomized trials of statin and placebo can determine whether the myalgia is actually due to the statin.
For patients treated for low back pain, catastrophizing may predict the degree of pain and disability.
There is a significant association between low vitamin D status and markers of inflammation in elderly adults.
Source of funding for spinal research is significantly associated with study outcome and level of evidence.
Exposure to cigarette smoke (passive or active) is associated with lower bone mineral density (BMD) in the femoral neck and lumbar spine of men.
Regional anesthesia, including peripheral nerve block (PNB), does not increase the risk of inpatient falls (IFs) after total knee arthroplasty (TKA).
Anika Therapeutics received FDA marketing approval for Monovisc (sodium hyaluronate [NaHA] in phosphate buffered saline) for the treatment of osteoarthritis (OA) of the knee.
Fever during pregnancy is associated with adverse health outcomes for the offspring.
Pfizer announced that the FDA has approved a sNDA to update the current label of Xeljanz (tofacitinib citrate) tablets to include radiographic data from two Phase 3 studies, ORAL Scan and ORAL Start.
The FDA has accepted Auxilium's supplemental Biologics License Application (sBLA) for Xiaflex (collagenase clostridium histolyticum, or CCH) for the treatment of two Dupuytren's contracture (DC) cords concurrently.
For patients recovering from musculoskeletal trauma, psychological factors, especially catastrophic thinking, are associated with pain intensity and disability.
In chronic disabling occupational lumbar disorder (CDOLD), lumbar fusion outcomes can be improved if opioid dependence and excessive length of disability after surgery are controlled through care.
Obesity is associated with more complex supracondylar humeral fractures in children, as well as with a greater risk of postoperative complications.
For older patients, a home-based exercise program is beneficial after formal hip fracture rehabilitation has ended,
For patients undergoing lower-extremity arthroplasty, a mobile compression device is noninferior to pharmacological protocols for the prevention of venous thromboembolism.
The FDA announced the approval of Vimizim (elosulfase alfa; BioMarin) for the treatment of Mucopolysaccharidosis Type IVA (Morquio A syndrome).
For older men, walking is associated with reduced risk of hip fracture, with more walking and brisker walking correlating with greater risk reduction.
Higher preoperative levels of pain and anxiety may be risk factors for chronic postsurgical pain for patients with adolescent idiopathic scoliosis (AIS) undergoing posterior spinal fusion.
For patients discharged from inpatient rehabilitation facilities, 30-day readmission rates are 11.8% overall.
Pennsaid (diclofenac sodium; Mallinckrodt) topical solution 2% w/w is now available.
Patients with or without diabetes experienced similar outcomes of laminoplasty for cervical spondylotic myelopathy.
Patients with back pain and degenerative disc disease (DDD) have different patterns of lumbar disc degeneration than patients with disc prolapse (DP).
Researchers have developed the first evidence-based diagnostic criteria for temporomandibular disorders (TMD).
A new model can predict the risk of medical complications, including major complications, after spine surgery.
Marital history, including disruptions and age at marriage, is associated with bone health in men, while marital support correlates with bone health in women.
For patients undergoing spinal fusion for adolescent idiopathic scoliosis (AIS), low body mass index (BMI) is associated with greater percent correction of thoracic curves.
Medac Pharma announced that the FDA has accepted for review its New Drug Application (NDA) for its lead product candidate MPI-2505 (methotrexate).
Hormone replacement therapy use (HRT) is associated with a reduction in revision rates for total knee arthroplasty (TKA) and total hip arthroplasty (THA).
The total economic cost to society for treatment of severe knee osteoarthritis is considerably lower with total knee arthroplasty than with nonoperative treatment.
The likelihood of experiencing worse pain at six months post-surgery is increased with a waiting time of 12 weeks or more for elective surgical lumbar discectomy (ESLD).
Most patients with spinal cord injury (SCI) have sleep disordered breathing (SDB).
The FDA has approved Mallinckrodt's NDA Pennsaid (diclofenac sodium) topical solution 2% w/w.
Childhood distal forearm fractures (DFFs) have two distinct etiologies.
The FDA has accepted for review the supplemental New Drug Application (sNDA) for Zorvolex (diclofenac; Iroko), a lower dose nonsteroidal anti-inflammatory drug (NSAID) for the treatment of osteoarthritis pain in adults.
Antares Pharma announced the availability of Otrexup (methotrexate for subcutaneous injection) for once-weekly self-administration with a single-dose disposable auto-injector.
Surgical hospitalization rates for lumbar spinal stenosis vary substantially across racial and ethnic groups.
Rates and patterns of shoulder injuries vary by sport and gender in high school athletes.
Researchers found that 60-day mortality rates significantly improved from 2004-2007 compared with 1989-1991.
For women from South China, breastfeeding is associated with reduced risk of rheumatoid arthritis (RA), especially a longer duration of breastfeeding.
Romosozumab seems safe and effective for increasing bone mineral density in postmenopausal women with low bone mineral density.
Mortality rates are higher in postmenopausal women with rheumatoid arthritis (RA) who have anti-cyclic citrullinated peptide (anti-CCP) antibodies.
Outcomes after arthroscopic partial meniscectomy are no better than outcomes after sham surgery in patients with knee symptoms due to an apparent degenerative medial meniscus tear.
The predictive ability for back injuries from manual handling was acceptable during the long term.
Evidence-based clinical guidelines have been developed for management of lumbar disc herniation with radiculopathy.
The FDA is advising consumers to immediately discontinue use of Mass Destruction, a dietary supplement marketed for muscle growth.
In 2011, 7.8 percent of components were implanted despite lack of evidence for clinical effectiveness.
Auxilium announced that it has submitted a supplemental Biologics License Application (sBLA) to the FDA for Xiaflex (collagenase clostridium histolyticum) for the treatment of multiple Dupuytren's contracture (DC) cords concurrently.
For patients undergoing spinal surgery for a structural lesion, preoperative depression and anxiety are associated with increased preoperative narcotic use.
For patients undergoing decompression for degenerative stenosis, the incidence of epidural hematoma is similar for different surgical approaches; however, there is a tendency toward increased postoperative hematoma in approaches with greater bony decompression area.
Patients admitted to the hospital on weekends for cervical spine fusion resulting from trauma have a greater length of stay and total hospital costs than their weekday counterparts.
The nerve root sedimentation sign, seen on magnetic resonance images, can differentiate lumbar spinal stenosis from asymptomatic controls.