After adjustment for potential confounders, exposed children had a 26% increased risk of ADHD compared with unexposed children.
More than two-thirds (85%) of those on sedatives and narcotics reported being counseled by a provider on the possibility of impaired driving.
The researchers found that good responders had higher mean MFQ summary scores at baseline and higher mean levels of suicidality than poor responders.
Researchers used Medicaid administrative claims data from 4 geographically diverse states to examine the impact of peer review PA policies on AAP use among Medicaid-insured youth.
The product is approved for the treatment of schizophrenia, acute treatment of manic and mixed episodes associated with bipolar I disorder and for use as an add-on treatment for depression in adults.
Results showed that cariprazine significantly delayed the time to relapse compared to placebo (P=0.0010). A total of 49.5% (n=49/99) of placebo treated patients relapsed vs. 29.7% (n=30/101) for the cariprazine treated patients.
In the subcohorts of patients with a diagnosis of bipolar disorder, continuing lithium was associated with decreased end-stage CKD, whereas continuing anticonvulsants was not.
The Hummingbird Phase 3 program included two Phase 3, multicenter, randomized, double-blind, parallel-group, placebo-controlled trials designed to evaluate the safety and effectiveness of brexanolone in women with moderate and severe PPD.
Completing more CCBT sessions was correlated with greater effect size improvements in mental health-related quality of life and symptoms.
The researchers found that there was a change in the 16-item Quick Inventory of Depression Symptomatology-Clinician Rated of −4.1 in the sertraline group and −4.2 in the placebo group.
Researchers conducted a prospective longitudinal cohort study of medical internship in the United States in which 3,121 interns (49.7% women) were recruited across all specialties from 44 medical institutions.
Results showed that 36 of the 39 participants experienced "a robust response" (decrease of QIDS total score by ≥50%) after 16.82 ± 6.26 treatments.
Following completion of all treatments 12 (52%) of the 23 subjects who initially met PTSD Checklist-Military (PCL-M) for diagnosis no longer met the threshold criteria.
The survey revealed that almost 40% of physicians would be reluctant to seek formal medical care for treatment of a mental health condition due to perceived repercussions to their medical licensure.
"The Treatment Initiation and Participation Program is an effective intervention to improve early adherence to pharmacotherapy," the authors write. "Improved adherence can promote improvement in depression."
Results showed that bupropion users were more likely to have a seizure, have accompanied tachycardia on presentation, and be admitted to the hospital, compared to those who ingested a TCA.
In the letter the FDA stated that their preliminary appraisal found that the sNDA was not sufficiently complete to permit a substantive review.
Researchers aimed to determine whether the rise in prescription drug use over time varied by age and obesity status.
Results found that overall depression was the most commonly reported adverse event in the VigiBase group while headaches were the most frequent adverse event reported for the Dutch database.
Researchers from the Perelman School of Medicine at the University of Pennsylvania analyzed 66 studies to determine the antidepressant effects of sleep deprivation.
Findings showed that almost all patients were 'much' to 'very much' improved clinically and in ratings of social function and academic performance.
On multivariable regression models, depression was a significant independent predictor of 30-day chest pain recurrence after adjustment.
Despite the abundance of evidence published in the past 40 years supporting lithium as an antisuicidal agent, its use is "underrepresented" and should be incorporated into clinical guidelines and practice more assertively.
The researchers observed an increase in the weighted percentage of U.S. adults making a recent suicide attempt from 0.62% in 2004 to 2005 to 0.79% in 2012 to 2013 (risk difference adjusted for age, sex, and race/ethnicity [ARD], 0.17%).
The researchers observed no correlation for panic disorder or GAD with maternal or neonatal complications of interest, in adjusted models.