Mood Disorders

CDC: Prevalence of Depression Examined Among U.S. Adults

February 14, 2018

Depression more common in women; lower among non-Hispanic Asians than other ethnic groups

Addressing Sensitive Topics With Patients: An Interview With Windel Stracener, MD

By February 14, 2018

"Patients must feel that you are empathetic and do not judge them. This is key not only to discussing weight, but to any subject that comes up," said Dr Windel Stracener, a family practitioner for 22 years.

Depression Treatment Initiation Among Newly Diagnosed 'Suboptimal', Says Study

By February 13, 2018

A total of 241,251 adults with newly diagnosed depression were assessed for this study.

Cognitive Enhancement Therapy May Benefit Adults With Autism

February 13, 2018

Participants treated with CET were significantly more likely to gain competitive employment

Is Cranial Electrical Stimulation Effective for Pain, Depression, Anxiety?

February 13, 2018

In patients with anxiety and depression, low-strength evidence of a possible modest benefit was seen in 4 trials conducted more than 40 years ago and in one recent trial compared with sham treatments.

Prazosin and placebo exhibit similar efficacy in post-traumatic stress disorder: The PACT trial

February 12, 2018

In patients with nocturnal symptoms of post-traumatic stress disorder (PTSD), prazosin did not significantly reduce nightmares or improve quality of sleep compared to placebo at 10 or 26 weeks.

Acne Linked to Significantly Higher Risk of Major Depressive Disorder

February 09, 2018

The researchers found that the probability of developing MDD was 18.5 and 12% among patients with acne and in the general population without acne over the 15-year follow-up period.

Novel Therapy for Major Depressive Disorder Gets Breakthrough Designation

By February 08, 2018

The Breakthrough Therapy designation is intended to offer a potentially expedited development path and review for promising drug candidates.

He Said, She Said: Clinician Sued After Patient Suffers Severe Drug Reaction

By February 07, 2018

It is essential to document warnings, especially significant ones, like this.

To What Extent Can Postnatal Depression Impact Child Behavior?

February 02, 2018

For mothers with moderate, marked, and severe PND, the odds ratios for child behavioral disturbance were 2.22, 1.91, and 2.39, respectively.

NDA for Novel Major Depressive Disorder Treatment Submitted to FDA

By January 31, 2018

The NDA submission is based on a comprehensive clinical efficacy and safety package with data from more than 30 clinical trials.

Are Psychiatric Drugs Being Overprescribed in Children and Adolescents?

By January 30, 2018

"Our results show that, at a population level, prescriptions of stimulants and antidepressant medications for children and adolescents do not appear to be prescribed at rates higher than the known rates for psychiatric conditions they are designed to treat," said the study's lead author, Dr. Ryan Sultan.

Specific White Matter Patterns Linked to Youth Psychopathology

January 29, 2018

The feature most associated with both of these traits was a brain white matter pattern reflecting frontotemporal connectivity and crossing fibers in the uncinate fasciculus.

Written Exposure Therapy Found to Be Effective for PTSD

January 24, 2018

The 24-week assessment showed the largest difference between treatments. The WET group had significantly fewer dropouts than the CPT group (4 versus 25).

Greater Pediatric, Public Health Interaction Needed for Failing Child Care

January 23, 2018

Pediatricians and public health professionals frequently interact to the benefit of children and their families; however, increasing integration of the two disciplines is critical for improving child health.

Significant Links Between Depressive Symptoms and Mortality in CA Patients

January 23, 2018

The researchers found that greater depressive symptoms were associated with significantly shorter survival (hazard ratio, 0.868; P<0.001), higher rates of chemoradiation interruption (odds ratio, 0.865; P=0.010).

Number of Adults Seeking Mental Health Specialty Care Increasing

January 12, 2018

The researchers found that between 2008 to 2009 and 2014 to 2015 the number of U.S. adults who received specialty outpatient mental health care rose from 11.3 million to 13.7 million per year/

Bidirectional Links Between Depression, Severe Dysglycemia Evaluated in T1D

January 05, 2018

Depression was strongly associated with increased risk of severe hyperglycemic and hypoglycemic events.

PMS/PMDD: A Review of Treatment Options

By January 04, 2018

Recent data regarding the treatment of premenstrual syndrome/premenstrual dysphoric disorder (PMS/PMDD) has "triaged therapy options into first, second, third, and last lines."

TCA-Induced Delirium in a Young Patient: Why Drug Titration Is Important

By January 04, 2018

Predisposing factors may contribute to delirium in patients taking tricyclic antidepressants.

Intranasal Esketamine Evaluated in Treatment-Resistant Depression

January 04, 2018

Change in Montgomery-sberg Depression Rating Scale score superior for esketamine versus placebo

Impact of Maternal Folate Status on Child's Autistic Traits After AED Exposure

By December 28, 2017

Children exposed to antiepileptic drugs (AEDs) in utero may have a reduced risk of autistic traits with periconceptional folic acid supplementation and folate status

Does Early Menarche Affect Mental Health in Adulthood?

December 27, 2017

Increased risk of depression, antisocial behaviors in adolescence may carry into adulthood

Positive Results Announced for Cariprazine in Bipolar Depression

By December 19, 2017

Results found that both groups had significantly greater improvements than placebo for the change from baseline to week 6 (P<0.05).

Ketamine May Have 'Rapid' Effect on Suicidal Ideation in Depressed Patients

By December 15, 2017

The ketamine-treated patients demonstrated a clinically significant reduction in suicidal thoughts compared to the midazolam-treated patients within 24 hours (4.96 points greater reduction in SSI, 95% CI: 2.33, 7.59).

Paternal SSRI Use Before Conception Linked to Offspring ADHD

December 11, 2017

After adjustment for potential confounders, exposed children had a 26% increased risk of ADHD compared with unexposed children.

Certain Drug Classes Tied to Less Frequent Driving Impairment Warnings

By December 01, 2017

More than two-thirds (85%) of those on sedatives and narcotics reported being counseled by a provider on the possibility of impaired driving.

Are Network Characteristics Prognostic for Long-Term Outcomes in Depression?

December 01, 2017

The researchers found that good responders had higher mean MFQ summary scores at baseline and higher mean levels of suicidality than poor responders.

Physician Burnout Associated With Significant Financial Costs

November 22, 2017

Economic loss at Stanford over two years expected to range from 15.5 million to 55.5 million

Impact of Psoriasis Treatments on Depressive Symptoms Examined

By November 20, 2017

Psoriasis patients may be at increased risk for depression and suicidality.