MONOPRIL

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Generic Name for MONOPRIL

Fosinopril sodium 10mg+, 20mg, 40mg; tabs; +scored.

Legal Classification:

Rx

Pharmacological Class for MONOPRIL

ACE inhibitor.

Manufacturer of MONOPRIL

Bristol-Myers Squibb

Indications for MONOPRIL

Hypertension.

Adult dose for MONOPRIL

Initially 10mg once daily. Usual maintenance: 20–40mg daily in single or 2 divided doses; max 80mg/day. If on diuretic: suspend diuretic for 2–3 days before starting if possible; resume diuretic if pressure not controlled with fosinopril alone. If diuretic cannot be discontinued: give 10mg and monitor carefully.

Children's dosing for MONOPRIL

<6yrs (≤50kg): not recommended. ≥6yrs (>50kg): 5–10mg once daily.

Contraindications for MONOPRIL

History of ACEI-associated or other angioedema. Pregnancy (Cat.D in 2nd and 3rd trimesters).

Warnings/Precautions for MONOPRIL

Salt/volume depletion. Renal or hepatic impairment. Monitor WBCs in renal or collagen vascular disease. CHF. Dialysis (esp. high-flux membrane). Renal artery stenosis. Monitor for hyperkalemia in diabetics. Discontinue if angioedema, laryngeal edema, jaundice, or markedly elevated liver enzymes occurs. Surgery. Pregnancy (Cat.C in 1st trimester). Nursing mothers: not recommended.

Interactions for MONOPRIL

Potentiated by diuretics. Potassium or K+-sparing diuretics may cause hyperkalemia. May increase lithium levels. Separate antacid dosing by 2 hrs. May cause false low serum digoxin measurements.

Adverse Reactions for MONOPRIL

Headache, cough, dizziness, GI upset, hyperkalemia, orthostatic hypotension, angioneurotic edema (discontinue if occurs).

How is MONOPRIL supplied?

Tabs 10mg, 20mg—30, 90, 1000
40mg—30, 90

Related Disease:

Hypertension

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