Miscellaneous Urologenital Disorders

Aggressive Control of BP, Lipids in T2DM May Up Kidney Risk

November 02, 2018

"We believe that the data actually suggest possible benefit for ESKD [end-stage kidney disease] with intensive glucose control, and remain inconclusive for intensive blood pressure control and fibrate use given the wide confidence intervals for the more reliable ESKD outcomes," write the authors.

High-Dose Flu Vaccine May Cut Hospitalization in Dialysis Patients

October 24, 2018

The researchers found that by vaccine type, the adjusted rates of first hospitalization were 8.43, 7.88, and 7.99 per 100 patient-months, respectively, and rates for death were 1.00, 0.97, and 1.04, respectively; these differences were not significant.

Good Outcomes for HCV-Negative Recipients of HCV Kidneys

August 07, 2018

"In summary, this trial provides reassuring (albeit preliminary) evidence that kidneys from HCV-infected donors may be safely transplanted into HCV-negative recipients," the authors write.

Midstream Urine Microbiome Diverse in Seniors With CKD

May 14, 2018

The remaining samples lacked a dominant genus. High levels of diversity were seen in the samples, as measured by the inverse Simpson, Chao, and Shannon indices.

Gestational Diabetes May Indicate Future Subclinical Renal Issues

May 10, 2018

Women with a history of gestational diabetes had significantly higher estimated glomerular filtration rate, even if they had not subsequently developed diabetes.

Alcohol Intake May Influence Oral Microbiome Composition

April 24, 2018

Subjects with higher alcohol consumption had certain genera that were enriched, including Actinomyces, Leptotrichia, Cardiobacterium, and Neisseria; some of these genera contain oral pathogens, and Neisseria can synthesize alcetaldehyde from ethanol.

Medicare pre-ESRD care results in more dialysis initiation but also increased two-year mortality

April 18, 2018

Veterans receiving pre-end stage renal disease (ESRD) nephrology care in under the Medicare system were more likely to undergo dialysis and had a higher two-year mortality rate than veterans that received pre-ESRD care through the Department of Veteran's Affairs (VA).

ZIKV RNA Often ID'd in Semen of Men With Symptomatic Infection

April 12, 2018

The researchers detected ZIKV RNA in the urine of 4% of the men and in the semen of 33% of the men, including in semen samples of 61% of the men who were tested within 30 days after illness onset.

No benefit of sodium bicarbonate or acetylcysteine for prevention of complications after angiography

February 15, 2018

Amongst patients undergoing angiography, neither sodium bicarbonate nor acetylcysteine were effective in preventing a composite outcome of death, need for dialysis, or persistent kidney injury.

Congenital Adrenal Hyperplasia Treatment Granted Orphan Drug Status

By December 07, 2017

CAH is a rare endocrine disorder caused by genetic mutations which result in an inability to produce cortisol.

Lixivaptan Gets Orphan Drug Status for Autosomal Dominant PKD

By October 05, 2017

Lixivaptan is a potent, selective vasopressin V2 receptor antagonist which has been found to delay the progression of an autosomal dominant form of polycystic kidney disease.

Elevated Fibroblast Growth Factor 23 Not a Risk Factor in Early CKD

September 20, 2017

The risk for premature death increased by 62% and 42% for stage 3 CKD patients with vitamin D deficiency and elevated parathyroid hormone levels, respectively.

Significant Sperm Count Decline in Western Men, Says Study

By July 28, 2017

Overall, between 1973 and 2011 the decline amounted to 52.4% (−1.38; −2.02 to −0.74; P<0.001) in sperm concentration.

Value of Enhanced Recovery Protocol in Colon, Rectal Sx

July 11, 2017

Based on one retrospective review of 8 years of compliance, the strongest predictors of shorter length of stay were identified as no nasogastric tube, early mobilization, early oral nutrition, early removal of epidural and urinary catheter, and nonopioid analgesia.

Outcomes of Preventable Hospital-Acquired Complications Examined in CKD

May 01, 2017

Relative to patients without CKD or preventable HAC, the odds ratios for mortality during index hospitalization were 2.22, 5.26, and 9.56, respectively, for patients with CKD with no HAC, without CKD with HACs, and with CKD and HACs.

Sleep Disorder Tx May Have Knock-On Benefit to Nocturia Symptoms

March 28, 2017

After starting CPAP, nighttime urination was reduced in 65% patients who had to get up more than once during the night to urinate.

Smartphone App Can Measure Male Fertility with 98% Accuracy

By March 23, 2017

All current home use fertility devices measure sperm concentration only but not motility

New Recommendations Published for Managing Small Renal Masses

January 19, 2017

In a clinical practice guideline published online January 16 in the Journal of Clinical Oncology, recommendations are presented for the management of patients with small renal masses (SRMs).

CDC: Decline in Renal Failure Among Certain Ethnic Groups

January 11, 2017

Diabetes-related end-stage renal disease among Native American adults fell by more than half over almost 20 years, according to research published in the January 10 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Ledipasvir-Sofosbuvir Safety Assessed in Kidney Transplant Patients

November 16, 2016

For kidney transplant recipients with hepatitis C virus (HCV) genotype 1 or 4 infection, treatment with ledipasvir-sofosbuvir for 12 or 24 weeks is safe and efficacious.

Long-Term Study Investigates Any Vasectomy and Prostate CA Links

September 20, 2016

There is no connection between vasectomy and overall risk of prostate cancer or prostate cancer mortality, according to a study published online September 19 in the Journal of Clinical Oncology.