Miscellaneous Respiratory Disorders

Additional Recommendations for LAM Diagnosis and Management Issued

November 29, 2017

The researchers made conditional recommendations against making a clinical diagnosis of LAM for women who have cystic changes on high-resolution computed tomography of the chest characteristic of LAM, but who have no additional confirmatory features of LAM.

AASM: Position Statement on Home Sleep Apnea Testing

By October 16, 2017

HSATs are ordered by healthcare providers to help diagnosis obstructive sleep apnea (OSA) in adults.

Standard Guidelines Needed for Pulmonary Fibrosis Assessment Test

October 13, 2017

Development of nuanced standards designed specifically for IPF are needed given that there is increasing evidence and experience with its use in clinical trials.

Removing Behavioral Interventions May Up Inappropriate Antibiotic Prescribing

October 11, 2017

The researchers found that the rate of inappropriate antibiotic prescribing decreased in control clinics from 14.2 to 11.8% during the post-intervention period (absolute difference, −2.4%).

New Implant Approved for Moderate to Severe Central Sleep Apnea

By October 10, 2017

The implantable device works by stimulating a nerve in the chest that is involved in transmitting signals to the diaphragm to stimulate breathing.

Linhaliq NDA Granted Priority Review

By September 25, 2017

Linhaliq was previously granted Qualified Infectious Disease Product (QIDP) Designation and Fast Track designation for NCFBE with lung infections with P. aeruginosa.

Impact of CPAP Telemonitoring with Feedback on Adherence

September 19, 2017

"The use of CPAP telemonitoring with automated feedback messaging improved 90-day adherence in OSA patients," the authors wrote.

Race May Play Role in Antibiotic Rx Trends for Pediatric ARTI

September 06, 2017

The researchers found that 2.6% of the PED encounters for viral ARTIs resulted in patient receipt of antibiotics, including 4.3, 1.9, 2.6, and 2.9% of non-Hispanic white, non-Hispanic black, Hispanic, and other non-Hispanic children, respectively.

Regeneron to Discontinue Development of RSV Treatment

By August 14, 2017

The primary endpoint of RSV prevention - assessed through day 150 of treatment - was not significantly reached.

NDA Submitted for Non-Cystic Fibrosis Bronchiectasis Treatment

By August 11, 2017

Linhaliq (previously known as 'Pulmaquin') consists of a mixture of liposome encapsulated and unencapsulated ciprofloxacin. Linhaliq has previously been granted Orphan Drug status for the management of bronchiectasis.

Guaifenesin/Pseudoephedrine Intervention May Cut Antibiotic Rxs for Acute URTI

By August 03, 2017

Results found that at day 8 of the study, a significantly lower amount of patients receiving guaifenesin/pseudoephedrine desired antibiotics compared to placebo, 4.2% vs. 8.0%, respectively.

'Overfat' Pandemic Grows Even as Obesity Rates Level Off

July 25, 2017

Traditional methods of measuring weight or body mass index are ineffective in assessing whether a person is overfat, the study authors said.

Cephalosporin Antibiotic Formulation Discontinued

By July 24, 2017

Specifically, the following presentations will no longer be available: 125mg/5mL; 100mL bottles (anticipated final date of availability: April 1, 2018), 250mg/5mL; 50mL bottles (anticipated final date of availability: January 15, 2018), 250mg/5mL; 100mL bottles (anticipated final date of availability: February 15, 2018)

Study Shows Zero Occurrences of Stethoscope Hygiene Between Patients

By July 19, 2017

Even after the intervention, of 41 subsequent observations, the researchers still noted zero occurrences of stethoscope hygiene. Hand hygiene did increase but only slightly, to 63%.

Probiotics Show Little Efficacy in Protecting Infants

July 06, 2017

The average number of days missed was 11 for both groups. And based on parents' daily reports, there were no differences in cold symptoms, diarrhea, fever, or vomiting.

Genetics Should Play a Bigger Role in Clinical Decision-Making

June 21, 2017

As home genetic testing grows, patients will be bringing their results to physicians for reaction and response. Physicians will need to be proactively prepared.

Old Anti-Nausea Agent May Be Effective for Sleep Apnea

By June 07, 2017

"Expanded and pivotal clinical trials must still be conducted to fully establish the best approach to cannabinoid therapy in obstructive sleep apnea," said lead author Professor David Carley.

Diagnostic Patch Effectively IDs Sleep Apnea

By June 05, 2017

This lightweight skin-adhesive diagnostic patch is able to record nasal pressure, blood oxygen saturation, pulse, respiratory effort, sleep time, and body position.

Contraceptive ID'd as Culprit in Patient with Shortness of Breath, Chest Pain

By May 30, 2017

While IUD displacement has been discussed in the literature, the authors could not find a similar case which showed a displaced IUD reaching the diaphragm and causing chest pain.

Can IV Acetaminophen Reduce Post-Op Pain in Sinus Sx?

May 26, 2017

The results showed immediate relieve for the treatment group but as time went on the placebo group actually showed greater meaningful reductions in pain.

Severe Bronchial Injury Following Iron Pill Aspiration

By May 25, 2017

The patient presented to the emergency department 12 hours after choking while taking her iron supplement.

Drug-Induced Bronchospasm in Multiple Asthma Patients

By May 23, 2017

Cocaine is considered one of the most commonly abused drugs that could potentially induce acute respiratory failure.

Antibiotic Failure Rates Investigated in Community-Acquired Pneumonia

By May 22, 2017

The researchers found that the total treatment failure rate was 22.1%, defined as either the need to refill antibiotic prescriptions, antibiotic switch, ER visit or hospitalization within 30 days of receiving initial antibiotic prescription.

Trends in Sudden Unexpected Infant Death Rates Examined

May 16, 2017

Following a decline in the late 1990s, the overall rate remained stable after 2000 - 93.4 cases out of every 100,000 live births.

EAACI: Position Paper on Non-Allergic Rhinitis Management

May 11, 2017

The authors note that diagnosis of NAR is based on a detailed medical history and exclusion of clinically relevant sensitization to airborne allergens, and exclusion of clinical signs of rhinosinusitis.

Corticosteroid Tx Evaluated in Adults with Acute Sore Throat

April 18, 2017

At 48 hours, more patients receiving dexamethasone than placebo (35.4% vs 27.1%) had complete symptom resolution, which was also observed in patients not offered delayed antibiotics.

Does Early Hydrocortisone Tx Impair Neurodevelopment in Preemies?

April 05, 2017

No statistically significant difference in neurodevelopment at 2 with hydrocortisone, placebo

Can Supplement Lower Risk of Bronchopulmonary Dysplasia?

March 30, 2017

The researchers found that 49.1% of the 592 infants assigned to the DHA group and 43.9% of the 613 assigned to the control group were classified as having physiological bronchopulmonary dysplasia.

Telehealth Presents New Utilization Opportunities But at What Cost?

March 23, 2017

Eighty-eight percent of telehealth visits for ARI were new utilization; increase in net spending per user.

More Intensive Alveolar Strategy May Benefit Cardiac Sx Patients

March 23, 2017

The mean and median pulmonary complications score was 1.8 and 1.7, respectively, for the intensive recruitment strategy group, compared with 2.1 and 2.0, respectively, for the moderate strategy group.