Miscellaneous Respiratory Disorders

Harmful Internet "Challenges" and Teens: A Guide for Primary Care Providers

July 12, 2018

Discussions involving Internet challenges with children and adolescents should be as sensitive as those about sexuality and drug or alcohol use.

Aspirin Desensitization May Improve Alcohol-Induced Symptoms in AERD Patients

By July 11, 2018

In addition to respiratory sensitivity to aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), patients with AERD oftentimes experience an additional allergic reaction when drinking alcohol.

Is Short-Course Antibiotic Treatment for CAP Effective?

By July 11, 2018

To investigate what impact antibiotic treatment duration has on CAP outcomes, researchers from the Warren Alpert Medical School of Brown University conducted a search of various databases for studies comparing the safety and efficacy of treatment regimens lasting ≤6 days (short) and ≥7 days (long).

Physician Sued by Noncompliant Patient After Failing to Follow Up on Test

By July 10, 2018

Timely review and appropriate follow up on all patient reports is essential and must be part of a practice's routine.

Smoking Marijuana May Be Tied to Cough, Sputum Production

July 03, 2018

Insufficient evidence for link between marijuana and pulmonary function, obstructive lung disease

Zephyr Valve Approved for Treating Patients With Severe Emphysema

By July 02, 2018

The approval was based on results from a multicenter study (LIBERATE) of 190 patients with severe emphysema.

Adenoid, Tonsil Removal May Affect Later Respiratory Risks

June 08, 2018

Participants were evaluated in linked national registers up to 2009, and incidence of disease was examined up to age 30 years, with adjustment for 18 covariates.

Recombinant human pentraxin 2 slows the decline in lung function in idiopathic pulmonary fibrosis

June 07, 2018

The use of recombinant human pentraxin 2 vs placebo resulted in a slower decline in lung function over 28 weeks for patients with idiopathic pulmonary fibrosis.

Procalcitonin Assay Doesn't Cut Antibiotic Use in Lower RTI

May 23, 2018

Provision of assay doesn't result in less antibiotic use for suspected lower respiratory tract infection

Slower Decline in Lung Function With Anthocyanin Intake

May 22, 2018

Slower annual rates of decline were seen in FEV1 and FVC for participants with the highest quartile of anthocyanin intake (−9.8mL/year for both). The FEV1/FVC ratio decline was also slower for the highest versus the lowest quartile of anthocyanin intake (−0.02/year).

Two Novel Immune-Response Clusters Identified to RSV

May 18, 2018

"Distinct immune-response clusters during infant RSV infection and their association with risk of recurrent wheeze provide insights into the risk factors for and mechanisms of asthma development," the authors write.

Can 3-D Printing Create Temporary Prosthesis, Cut Out Prosthodontist?

May 15, 2018

Evaluators were able to match the correct 3-D nose to the corresponding volunteers' photographs in 171 of 175 photographs (97.7%).

FDA Targets Clinics Offering Unapproved Stem Cell Therapies

May 11, 2018

The clinic claims its unapproved therapies can treat a number of serious diseases and conditions, including Parkinson's disease, amyotrophic lateral sclerosis (ALS), chronic obstructive pulmonary disease (COPD), heart disease, and pulmonary fibrosis.

Novel Thirdhand Smoke Exposure Route Identified

May 11, 2018

The chemical residue from cigarette smoke that attaches to anything and anyone in the vicinity of a smoke cloud, can still make its way into the air of buildings that currently have a non-smoking designation.

AASM: Medical Marijuana Should Not Be Used to Treat Sleep Apnea

By April 16, 2018

Continuous positive airway pressure (CPAP) remains the mainstay of medical treatment for OSA.

Caffeine Therapy for Apnea of Prematurity Safe Over Long Term

April 11, 2018

Compared to the placebo group, the caffeine group performed better in fine motor coordination (P=0.01), visuomotor integration (P<0.05), visual perception (P=0.02), and visuospatial organization (P=0.003).

Treatment for Idiopathic Pulmonary Fibrosis Gets Orphan Drug Designation

By April 10, 2018

RP5063 is a new chemical entity with a novel mechanism of multimodal modulation of serotonin and dopamine signaling pathways.

Sirolimus May Be Beneficial in DIPNECH Syndrome

April 10, 2018

The patients began treatment with oral sirolimus; after 1 year of treatment, there was improvement in exertional dyspnea in all 3 patients.

"Condom Challenge" Growing in Popularity Among Teens

By April 03, 2018

"As graphic as it is, we have to show parents because teens are going online looking for challenges and recreating them," said education specialist Stephen Enriquez.

Nintedanib Fast Tracked for ILD-Associated Scleroderma

By March 19, 2018

The designation was supported by the Investigational New Drug application (IND) for the treatment of SSc-ILD and the anticipated safety and efficacy data from the Phase 3 double-blind, randomized, placebo-controlled SENSCIS trial.

Cluster of Idiopathic Pulmonary Fibrosis Cases ID'd Among Dentists

By March 14, 2018

Some substances used while conducting these tasks contained silica, polyvinyl siloxane, alginate, and other compounds with known or potential respiratory toxicity.

Pediatric Airflow Obstruction and Tobacco Smoke Exposure: Is There a Link?

March 09, 2018

Serum cotinine level was not significantly associated with airflow obstruction in the multivariate analysis with both exposures included as covariates (adjusted odds ratio, 1.07; 95% confidence interval, 0.94 to 1.21); there was no correlation in children with asthma or those without asthma.

FDA Accepts Solriamfetol NDA for Narcolepsy-, OSA-Related Sleepiness

By March 02, 2018

Solriamfetol is a selective dopamine and norepinephrine reuptake inhibitor.

Undergoing Cardiac Sx During Flu Season May Increase Respiratory Disease Odds

February 22, 2018

Researchers found that ARDS developed in 5.1% of the 740 patients who were admitted to the intensive care unit after cardiac surgery during baseline periods. ARDS developed in 5.6% of the 984 patients in the periods between baseline and influenza seasons and in 9% of the 289 patients during influenza seasons.

Cleaning Could Impact Respiratory Health

February 21, 2018

The researchers found that forced expiratory volume in 1 second (FEV1) declined more rapidly in women responsible for cleaning at home and occupational cleaners compared to women not engaged in cleaning.

Study Reveals Factors Linked to Inappropriate Antibiotic Prescribing

February 05, 2018

Adult patients seen by an advanced practice practitioner were 15% more likely to receive an antimicrobial compared to those seen by a physician provider, after adjustment.

Greater rates of mortality linked to infants at risk for maltreatment

January 29, 2018

Infants classified as very high risk for substantiated maltreatment had a higher relative risk of overall mortality, death through unintentional and inflicted injury, and sudden unexpected infant death.

Pre-Op Physical Therapy May Cut Pulmonary Complications

January 29, 2018

The absolute risk reduction was 15%, with the number needed to treat of 7

Forceful Sneeze Leads to Rare, but Serious Injury

By January 17, 2018

The man explained how he suppressed a sneeze by pinching his nostrils and keeping his mouth closed, and then felt a popping sensation in his neck.

Detection of respiratory viruses in febrile infants suggests lower risk of bacterial infection

January 17, 2018

Respiratory viruses were identified in 55% of febrile infants; those older than 28 days had a lower risk of bacterial infection when they tested positive for a respiratory virus.