Miscellaneous Ob/Gyn Conditions
The researchers found that FIR ≥15% correlated with an increased risk of the composite primary outcome (odds ratio, 4.38) and preeclampsia (odds ratio, 6.76), and was more common among women with type 1 diabetes (36.6 versus 14.5%)
Over the study period, smoking during pregnancy increased significantly among women with MDE (35.9 to 38.4%; P=0.02), while a decreasing trend among women without MDE only approached statistical significance (12.5 to 9.1%; P=0.07).
Leiomyomas, age younger than 35 years, at least 2 prior cesarean deliveries, and history of sterilization were factors that predisposed patients to post-ablation hysterectomy.
The researchers found that 318 of the 470 women in the database met inclusion criteria. Nineteen women (6%) had viral load rebound with a mean log10 viral load near delivery of 2.71 copies/mL (=513 copies/mL), while 6 women (32%) had a viral load above 1,000 copies/mL.
The researchers found that, compared to the 50 women with no vaccination in the previous year, the 91 women vaccinated the prior year exhibited higher baseline antibody titers and/or seroprotection rates against all four influenza strains, after controlling for covariates.
The researchers observed variation in the absolute risk for neonatal drug withdrawal from 1.0 to 11.4% for infants exposed in utero to prescription opioids alone and opioids co-prescribed with gabapentin, respectively.
The authors noted that there may be a select group of women who make an informed choice of medically supervised withdrawal, which should be under the care of an experienced physician and include long-term follow-up and support to help prevent relapse.
The researchers found that, overall, interventions were associated with a 9% reduction in risk of cesarean section, and a 24% reduction in risk of developing gestational diabetes.
"Importantly, the absolute risk of autism was small, and, hypothetically, if no pregnant women took antidepressants, the number of cases that could potentially be prevented would be small," wrote the authors of the study.
Commenting on the report, retired Ob-Gyn Valerie Anne Jones, MD said, "Access to maternity care and women's health services is vitally important, and we need to have infrastructure to support the numbers or these women will have no Ob-Gyn to turn to despite having insurance."
The data showed in utero exposure to clindamycin was associated with a higher risk of MCMs (adjusted odds ratio [aOR] 1.34, 95% CI: 1.02-1.77), musculoskeletal system malformations (aOR 1.67, 95% CI: 1.12-2.48), and ventricular/atrial septal defect (aOR 1.81, 95% CI: 1.04-3.16).
The team found that higher sugar-sweetened beverage intake during the second trimester of pregnancy was associated with greater adiposity in mid-childhood.
While the clinicians could not rule out the possibility of transmission from a colonized household member, their final diagnosis was late-onset GBS disease attributable to high maternal colonization secondary to consumption of GBS-infected placental tissue.
CDC researchers used birth records for nearly 100% of the births in the United States in 2016. The teen birth rate was 20.3 births per 1,000 female teens in 2016, compared to 41.5 births per 1,000 in 2007, according to the report.
"The use of acupuncture with or without clomiphene, compared with control acupuncture and placebo, did not increase live births," the authors write.
The patient was a 32-year-old nulliparous white female who reported a 5-year history of severe hypertension, hypokalemia, and resultant systolic dysfunction.
The researchers found that fetal demise, preterm birth, and neonatal intensive care unit (NICU) admissions occurred in 15.6, 46.3, and 59% of pregnancies, respectively.
The analysis found that the simulated maternal serum concentration associated with the lowest probability of infant cerebral palsy was 4.1mg/dL, while the simulated total administered magnesium dose associated with the lowest probability of delivering an infant with cerebral palsy was 64g.
The study was conducted in 1,000 women residing in the Republic of Ireland and Northern Ireland, where abortion is not available through the formal healthcare system.
Limited quality evidence is available for the effectiveness of domperidone in enhancement of lactation, while considerable evidence is available on the cardiac risks associated with domperidone, which include QT prolongation, torsades de pointes, and sudden cardiac death.
The FDA has issued a Complete Response Letter (CRL) to the New Drug Application (NDA) of TX-004HR (TherapeuticsMD) for the treatment of moderate-to-severe vaginal pain during sexual intercourse (dyspareunia), a symptom of vulvar and vaginal atrophy (VVA) due to menopause.
The investigators found that 27.7% of beneficial bacteria in a baby's intestinal tract come directly from the mother's milk, and 10.3% comes from areolar skin.
The researchers found that both groups experienced a significant improvement of dyspareunia, with no difference between the groups.
"The findings highlight the likelihood that prenatal exposure to progesterone may have a long-term influence on behavior related to sexuality in humans," said lead researcher June Reinisch, Director Emerita of The Kinsey Institute.