Miscellaneous Musculoskeletal Disorders
Octagam 10% is currently approved to treat chronic immune thrombocytopenic purpura (ITP) in adult patients. It is supplied as 2g, 5g, 10g, or 20g single-use bottles.
A new review published in the Journal of Neurosurgery: Spine details the health issues that troubled JFK the most, specifically his back. His low-back pain was instigated by a football injury sustained while he was at Harvard in 1937. An orthopedic spine specialist diagnosed him in 1940 with a "very unstable lumbosacral joint".
Results showed a statistically significantly, but not a clinically important, improvement in two of the trials which evaluated radiofrequency denervation for the sacroiliac joints (−0.71 (95% CI, −1.35 to −0.06) and a combination of the facet joints, sacroiliac joints or intervertebral disks (−0.99 (95% CI, −1.73 to −0.25) at 3 months.
Virtual reality is much more than just a new form of entertainment, it is increasingly being used in a wide range of medical applications.
The analysis of nationwide data from 2004 to 2009 found that patients with back pain who screened positive for depression were more than twice as likely to be prescribed an opioid.
The data showed sarcopenia was 4 times more prevalent for the high-risk alcohol drinking group vs. the low-risk alcohol drinking group (odds ratio 4.29, 95% CI: 1.87, 9.82).
Initially, the team attributed the muscle weakness to either HIV or drug-mediated myopathy but a muscle biopsy later revealed atrophy of type II fibers without necrosis or inflammation.
In preclinical studies, AMO-02 has shown efficacy in transgenic models and reversal of muscle cell differentiation deficits in ex vivo tissue samples.
Practitioners can evaluate a patient for exercise addiction by exploring a patient's motivation for exercise, determining whether they cut back when injured, exploring the patient's emotional connection to exercise, and assessing whether exercise interferes with other aspects of life.
The CHERISH study was a multicenter, randomized, double-blind, sham-procedure controlled study to evaluate the safety and efficacy of Spinraza in children with later-onset SMA (n=126) aged 2-12 years.
The researchers concluded that stimulant drug use may result in acute stimulant-induced tremor as well as long-term proprioceptive deficits in terms of arm-droop.
The FDA approval was based on efficacy data of Ingrezza in a 6-week clinical study (n=234) of patients who received Ingrezza vs. placebo.
Researchers provided 30 patients who'd had spinal fusion surgery with a 30-minute music therapy session within 72 hours of their operation, while another group received only standard care after their procedure.
The researchers identified an additional 24 published studies and 25 unpublished studies, since the last completed systematic review of 57 eligible studies.
The researchers found that percentage of responders (LBP intensity <40 on an 11-point numerical rating scale) was higher in the GC IDI group than the control group at one month after the intervention.
One study found that patients who are discharged directly home following a total knee arthroplasty face a lower risk for complications and hospital readmission than those who first go to an inpatient rehab facility.
Prediction of subsequent PsA was associated with baseline presence of arthralgia in women (hazard ratio [HR], 2.59), heel pain (HR, 4.18), high fatigue score (HR, 2.36), and high stiffness score (HR, 2.03).
The patient presented with complaints of increased muscle tone in her back muscles and the right side of her body starting in adolescence.
The submission is supported by data from the Phase 3 REGAIN study, a randomized, double-blind, placebo-controlled trial which enrolled a total of 125 patients with anti-AChR Abs.
Patients and physicians have substantially different goals when it comes to chronic musculoskeletal pain management, however these differences do not predict patient experience or physician-reported visit difficulty.
The Food and Drug Administration (FDA) has granted Orphan Drug designation to Resolaris (aTyr Pharma) for the treatment of limb girdle muscular dystrophy (LGMD).
In the U.S., diazepam is prescribed in approximately 300,000 visits for low back pain annually, however the evidence regarding its efficacy is surprisingly lacking.
For patients experiencing low back pain, yoga may be an effective pain reliever, according to a review published online January 12 in The Cochrane Library.
The Food and Drug Administration (FDA) has approved Emflaza (deflazacort; Marathon) tablets and oral suspension for the treatment of Duchenne muscular dystrophy (DMD) in patients aged 5 years and older.
Older adults who take multiple medications may be twice as likely to become frail in a relatively short period of time (3 years) compared to those who take fewer medications.
Low back pain is common in school-age American children, and rates increase with age, according to a study published online January 30 in JAMA Pediatrics.