Miscellaneous Musculoskeletal Disorders

USPSTF Issues New Fall Prevention Recommendations

September 27, 2017

Multifactorial interventions to prevent falls should be offered selectively by clinicians; the overall net benefit of routinely offering multifactorial interventions is small.

Limiting Sedentary Time 'Necessary' to Avoid Mobility Loss

August 31, 2017

At the study's end, 29% of participants were either unable to walk or had difficulty doing so.

Octagam 10% Gains Orphan Drug Status for Rare Muscle, Skin Disorder

July 17, 2017

Octagam 10% is currently approved to treat chronic immune thrombocytopenic purpura (ITP) in adult patients. It is supplied as 2g, 5g, 10g, or 20g single-use bottles.

Research Paper Reviews JFK's Chronic Health Issues

By July 14, 2017

A new review published in the Journal of Neurosurgery: Spine details the health issues that troubled JFK the most, specifically his back. His low-back pain was instigated by a football injury sustained while he was at Harvard in 1937. An orthopedic spine specialist diagnosed him in 1940 with a "very unstable lumbosacral joint".

Is Radiofrequency Denervation Effective for Chronic Low Back Pain?

By July 05, 2017

Results showed a statistically significantly, but not a clinically important, improvement in two of the trials which evaluated radiofrequency denervation for the sacroiliac joints (−0.71 (95% CI, −1.35 to −0.06) and a combination of the facet joints, sacroiliac joints or intervertebral disks (−0.99 (95% CI, −1.73 to −0.25) at 3 months.

From Treatment to Training: 5 Uses of Virtual Reality in Healthcare

June 27, 2017

Virtual reality is much more than just a new form of entertainment, it is increasingly being used in a wide range of medical applications.

Back Pain, Depression and Opioids: Research Uncovers Rx Pattern

June 23, 2017

The analysis of nationwide data from 2004 to 2009 found that patients with back pain who screened positive for depression were more than twice as likely to be prescribed an opioid.

Higher Alcohol Intake May Up Muscle Loss, Function for Some Women

By June 07, 2017

The data showed sarcopenia was 4 times more prevalent for the high-risk alcohol drinking group vs. the low-risk alcohol drinking group (odds ratio 4.29, 95% CI: 1.87, 9.82).

Case: Inhaled Corticosteroid-Induced Myopathy in HIV Patient

By May 26, 2017

Initially, the team attributed the muscle weakness to either HIV or drug-mediated myopathy but a muscle biopsy later revealed atrophy of type II fibers without necrosis or inflammation.

Fast Track Status Granted to Tideglusib for Myotonic Dystrophy

By May 17, 2017

In preclinical studies, AMO-02 has shown efficacy in transgenic models and reversal of muscle cell differentiation deficits in ex vivo tissue samples.

Are Statin Users at Greater Risk for Back Disorders?

By May 03, 2017

Previous research has demonstrated a link between statin use and use-related injury and arthropathies.

Review: Evaluating Patients for Primary Exercise Addiction

April 27, 2017

Practitioners can evaluate a patient for exercise addiction by exploring a patient's motivation for exercise, determining whether they cut back when injured, exploring the patient's emotional connection to exercise, and assessing whether exercise interferes with other aspects of life.

Spinraza Beneficial in Later-Onset Spinal Muscular Atrophy

By April 24, 2017

The CHERISH study was a multicenter, randomized, double-blind, sham-procedure controlled study to evaluate the safety and efficacy of Spinraza in children with later-onset SMA (n=126) aged 2-12 years.

Movement Disorders Examined in Current, Past Stimulant Drug Users

By April 21, 2017

The researchers concluded that stimulant drug use may result in acute stimulant-induced tremor as well as long-term proprioceptive deficits in terms of arm-droop.

First Drug for Tardive Dyskinesia Gains Approval

By April 12, 2017

The FDA approval was based on efficacy data of Ingrezza in a 6-week clinical study (n=234) of patients who received Ingrezza vs. placebo.

Music Therapy Relieves Post-Op Pain in Spinal Surgery Patients

April 10, 2017

Researchers provided 30 patients who'd had spinal fusion surgery with a 30-minute music therapy session within 72 hours of their operation, while another group received only standard care after their procedure.

Experimental Device Helps Paralyzed Man Feed Himself

March 29, 2017

Researchers utilized functional electric stimulation intracortical brain-computer interface system

Diabetic Peripheral Neuropathy Treatments Explored

March 27, 2017

The researchers identified an additional 24 published studies and 25 unpublished studies, since the last completed systematic review of 57 eligible studies.

Glucocorticoid Intradiscal Injection Evaluated for Low Back Pain Relief

March 21, 2017

The researchers found that percentage of responders (LBP intensity <40 on an 11-point numerical rating scale) was higher in the GC IDI group than the control group at one month after the intervention.

Is Direct Home Discharge Better for Arthroplasty Recovery?

March 17, 2017

One study found that patients who are discharged directly home following a total knee arthroplasty face a lower risk for complications and hospital readmission than those who first go to an inpatient rehab facility.

Musculoskeletal Symptoms May Precede PsA Diagnosis

March 13, 2017

Prediction of subsequent PsA was associated with baseline presence of arthralgia in women (hazard ratio [HR], 2.59), heel pain (HR, 4.18), high fatigue score (HR, 2.36), and high stiffness score (HR, 2.03).

Genetic Testing Abused by Patient with Factitious Disorder

By March 08, 2017

The patient presented with complaints of increased muscle tone in her back muscles and the right side of her body starting in adolescence.

Alexion Seeks Eculizumab Approval for Ultra-Rare Neuromuscular Disease

By March 08, 2017

The submission is supported by data from the Phase 3 REGAIN study, a randomized, double-blind, placebo-controlled trial which enrolled a total of 125 patients with anti-AChR Abs.

Pain Management Goals Differ for Physicians, Patients

By March 01, 2017

Patients and physicians have substantially different goals when it comes to chronic musculoskeletal pain management, however these differences do not predict patient experience or physician-reported visit difficulty.

Resolaris Granted Orphan Drug Status for Rare Genetic Myopathy

By February 28, 2017

The Food and Drug Administration (FDA) has granted Orphan Drug designation to Resolaris (aTyr Pharma) for the treatment of limb girdle muscular dystrophy (LGMD).

Low Back Pain Treatment Guidelines Released

By February 14, 2017

The recommendations are intended for all clinicians treating adult patients with acute, suabcute, or chronic low back pain.

Is Diazepam Beneficial in Acute Low Back Pain?

By February 13, 2017

In the U.S., diazepam is prescribed in approximately 300,000 visits for low back pain annually, however the evidence regarding its efficacy is surprisingly lacking.

Can Yoga Improve Nonspecific Low Back Pain, Function?

February 13, 2017

For patients experiencing low back pain, yoga may be an effective pain reliever, according to a review published online January 12 in The Cochrane Library.

Emflaza Approved for Duchenne Muscular Dystrophy

By February 10, 2017

The Food and Drug Administration (FDA) has approved Emflaza (deflazacort; Marathon) tablets and oral suspension for the treatment of Duchenne muscular dystrophy (DMD) in patients aged 5 years and older.