Miscellaneous Gastrohepatic Disorders

HCV Guidelines Updated to Include Recommendations for Key Populations

By May 25, 2018

The guidelines were developed by the American Association for the Study of Liver Diseases and the Infectious Diseases Society of America.

Opioids Often Overprescribed After Hiatal Hernia Surgery

May 03, 2018

Patients use fewer opioids than are prescribed after open, laparoscopic hiatal hernia repair

Factors ID'd to Predict Fatty Liver in Obese Teens

April 24, 2018

"The combination of ethnicity/race with markers of insulin resistance and genetic factors might help identify obese youth at risk for developing fatty liver," the authors write.

Optimizing organ donations from overdose deaths may help address national organ shortage

April 19, 2018

U.S. transplants using organs from overdose-death donors (ODDs) has increased 24-fold from 2000 to 2016, and transplant outcomes from organs donated by ODDs have been noninferior to those donated by trauma-death donors (TDDs) and medical-death donors (MDDs).

Oral Nitroglycerin Solution: An Effective Option for Esophageal Food Impaction?

By April 09, 2018

While glucagon is often used for the treatment of esophageal food impaction, its effectivess, based on several studies, has been inconsistent.

Obesity Can Negatively Affect Liver in Children As Young As 8

April 06, 2018

Each additional 10cm greater waist circumference at early childhood was associated with 1.99 higher odds of elevated ALT at mid-childhood, in multivariable-adjusted models.

Livantra Granted Orphan Drug Status for Acute-on-Chronic Liver Failure

By March 30, 2018

Livantra may help rate of survival without transplantation or help improve survival until patients can receive a new liver.

Liver Disease, Insulin Resistance Associated With High Red Meat Consumption

March 20, 2018

The researchers found that after adjusting for body mass index, physical activity, smoking, alcohol, energy, saturated fat and cholesterol intake, the odds of NAFLD and IR were increased in association with high consumption of total meat.

Does Gut Bacteria Translocate to the Brain During Sepsis?

March 15, 2018

Among humans who died of sepsis, bacterial taxa detected in their brains were distinct from those who died of noninfectious causes and were correlated with S100A8/A9 expression.

Hyperandrogenism May Impact Gut in Polycystic Ovary Syndrome

January 24, 2018

There was a change in alpha diversity of women with PCOM that was intermediate between the other two groups. Regression analyses revealed a negative correlation of hyperandrogenism, total testosterone, and hirsutism with alpha diversity.

Triple Therapy Linked to Mortality Rate in CAD With GI Bleeding

December 06, 2017

Increased mortality at 90 days in patients with lower gastrointestinal bleeding, coronary artery disease

Frequency of Celiac Disease Testing Examined in Patients with IDA

By November 30, 2017

The subgroup that was most frequently tested was young Caucasian men, with 61% of respondents stating that they would implement serologic testing in this group.

Long-Term Aspirin Use Linked to Reduced Incidence of GI Cancers

By October 31, 2017

Researchers compared patients who were prescribed aspirin over a long period (for at least six months, average duration of aspirin prescribed was 7.7 years) with non-aspirin users and assessed the incidences of a number of cancers.

Intrahepatic Cholestasis Following Regular Consumption of Herbal Tea

By October 17, 2017

The case involved a 30-year-old female with a history of anxiety and migraine who presented with complaints of malaise, right upper quadrant pain, worsening jaundice, dark colored urine, and itching; these symptoms had been going on for a few weeks.

ACG: Prevalence of Burnout Examined Among Gastroenterologists

October 16, 2017

Factors associated with burnout include female sex, spending more hours on domestic chores, child care

Early-Life Antibiotic Use and Celiac Disease: Is There an Association?

October 10, 2017

The researchers found that exposure to and frequency of use of any antibiotic assessed in the study in early life or before seroconversion was not associated with the risk of developing islet or celiac disease autoimmunity.

Antibiotic Class Linked to Increased Risk of GI Perforation

By September 18, 2017

The researchers compared a cohort of 17,510 individuals diagnosed with GI perforation to a matched group of 1,751,000 controls.

What Are the Clinical Characteristics of Hepatic Sarcoidosis?

By September 18, 2017

Most patients were asymptomatic and the diagnosis was discovered in pursuit of other abnormal biochemical tests and imaging studies. In the majority of patients, alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) were elevated (88 and 90%, respectively).

Treating HCV Infection May Prevent Development of Chronic Kidney Disease

By September 18, 2017

Using several databases, the researchers examined the association of HCV infection with the incidence of CKD.

Statins May Lower the Risk of Premature Death in Alcoholic Cirrhosis

By September 08, 2017

Results found that mortality rates were 88 (95% CI; 73-105) per 1,000 years for patients using statins and 127 (95% CI; 114-141) for non-statin patients, the hazard ratio was 0.57 (95% CI; 0.41-0.71).

Celiac Disease Linked to Increased Risk of Pneumococcal Infection

By August 15, 2017

After adjusting for socioeconomic index, diabetes, level of education, sex and age, an increased risk of pneumococcal infection among celiac disease patients was noted.

Value of Enhanced Recovery Protocol in Colon, Rectal Sx

July 11, 2017

Based on one retrospective review of 8 years of compliance, the strongest predictors of shorter length of stay were identified as no nasogastric tube, early mobilization, early oral nutrition, early removal of epidural and urinary catheter, and nonopioid analgesia.

FDA, CDC: Hepatitis A Linked to Contaminated Fish

By June 02, 2017

The tuna, sourced from Sustainable Seafood Company, Vietnam, and Santa Cruz Seafood Inc., Philippines, was shipped to the U.S. and may potentially have been used by establishments in Texas, Oklahoma, and California.

CDC: Severe Toxicity, Liver Transplants Following Mushroom Poisonings

By June 01, 2017

Amatoxins, the principle toxic alkaloids found in these mushrooms, account for over 90% of deaths related to mushroom poisonings.

First-of-its-Kind Device Cleared to Treat Esophageal Birth Defect

By May 12, 2017

All 16 infants in the clinical trial of the device demonstrated a successful joining of their esophagus within 3-10 days after receiving it.

Novel Treatment for IgG4-Related Disease Gains Orphan Drug Status

By May 12, 2017

There is currently no approved treatment for lgG4-RD, which is a newly recognized disorder and is estimated to affect 40,000 individuals in the U.S.

Important Information for Clinicians Prescribing Sucraid

By May 04, 2017

The FDA is recommending that clinicians prioritize access to the unapproved lot of Sucraid for patients with severe CSID and for patients with evidence of malnutrition.

Gluten Consumption and CVD Risk: What's the Link?

May 04, 2017

For the vast majority of people who can tolerate it, restricting gluten to improve your overall health is likely not to be a beneficial strategy, found the authors.

Report Sheds Light on Physician Compensation by Location, Gender

By April 26, 2017

Which cities report the highest physician compensation?

Propofol Use Linked to Rare Case of Fatal Pancreatitis

April 26, 2017

57-year-old woman developed severe abdominal pain with nausea, vomiting after thyroidectomy