Miscellaneous Dermatological Disorders
Of those with allergic reactions, 32 patients exhibited significant deterioration of AD. Compared to nonresponders, responders showed significantly higher specific immunoglobulin E (IgE) levels to birch pollen and apple in addition to a higher prevalence of allergic rhinoconjunctivitis.
The FDA approval was supported by two Phase 3 studies that demonstrated the safety and efficacy of Eskata for the treatment of raised seborrheic keratoses.
Researchers assessed the long-term safety results from a multicenter, open-label, 48-week safety study of 517 patients ≥2 years of age with mild to moderate AD who continued crisaborole treatment after completing a 28-day phase 3 pivotal study.
Current treatments for Hailey-Hailey disease, a severe genetic blistering disease of intertriginous skin, have led to varied clinical outcomes with potentially severe side effects.
The researchers found that blinded investigator-rated healing was better for the tripeptide/hexapeptide system, with the difference reaching statistical significance at day 7.
The researchers found that for treatment of overactive bladder, the safety and efficacy of intradetrusor injection of onabotulinumtoxin A is sensitive to injection volume and depth.
Climbazole enhances retinoid-associated biological activities in vivo and in vitro, according to a study published online January 19 in the International Journal of Cosmetic Science.
Allergan has announced the availability of Juvèderm Volbella XC for lip augmentation and for correction of perioral rhytids in adults over the age of 21.
The Food and Drug Administration has granted Orphan Drug designation to TXA127 (Tarix Orphan) for the potential treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB), a rare genetic skin disorder.
For children with atopic dermatitis, clinical scores for sleep loss, pruritus, disease severity, and quality of life correlate well.
Fractional high-intensity focused radiofrequency (HiFR) delivered to the dermis is effective for skin laxity of the lower face/neck, according to a study published in Lasers in Surgery and Medicine.
The rate of revision septorhinoplasty is 3.3%, and specific patient characteristics correlate with increased revision rates, according to research published online in JAMA Facial Plastic Surgery.