Miscellaneous Dermatological Conditions

Positive Results for Dupilumab in Teen Atopic Dermatitis Trial

By May 16, 2018

The primary endpoint was the proportion of patients with an IGA score of 0 (clear) or 1 (almost clear) at Week 16.

Topical Treatment for Epidermolysis Bullosa Gets FDA's Rare Pediatric Designation

By May 16, 2018

A previous Phase 2 trial of 17 patients with EBS showed that 60% of those treated with diacerein cream experienced at least a 40% reduction in blistering after 4 weeks vs 18% on vehicle.

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Causes, Treatment Investigated

By May 15, 2018

The multicenter retrospective study (N=377) was conducted to investigate the causes, treatment protocols, and mortality rates of US adults with SJS/TEN.

Can 3-D Printing Create Temporary Prosthesis, Cut Out Prosthodontist?

May 15, 2018

Evaluators were able to match the correct 3-D nose to the corresponding volunteers' photographs in 171 of 175 photographs (97.7%).

Teledermatology Could Expedite Care for Suspected Skin Cancer

May 14, 2018

The researchers found that the mean time to clinical resolution was 9 days with teledermoscopy referral, compared with 35 days with usual care alone.

Adverse Effect of Osteoporosis Drug May Help Treat Hair Loss

By May 11, 2018

Researchers found that a non-immunosuppressant drug originally designed to treat osteoporosis (WAY-316606) targeted the same mechanism by antagonizing SFRP1, and after treating hair follicles with WAY-316606 for 6 days, the authors found enhanced human hair growth.

Eskata Now Available to Treat Raised Seborrheic Keratoses

By May 07, 2018

Eskata is a high-concentration hydrogen peroxide-based topical solution intended for in-office application.

Hyaluronidase Can Remove Hyaluronic Acid Fillers in Cosmetic Dermatology

April 27, 2018

The researchers found that at 4 weeks and 4 months there were significant differences in physician rater assessment for visual detection and palpability between saline and hyaluronidase; this was mirrored by participant self-assessment at 4 weeks and 4 months.

Serlopitant Found to Be Safe, Effective for Chronic Pruritus

April 24, 2018

The decreases from baseline using visual analogue scale pruritus scores were statistically significantly larger with the 1- and 5-mg doses of serlopitant (P=.022 and .013, respectively) versus placebo at week 6.

Vaniqa Cream Currently in Shortage

By April 18, 2018

Vaniqa, a hair growth retardant, is indicated to reduce unwanted facial hair in women.

Endocrine Therapy-Induced Alopecia Seen in Breast Cancer

April 12, 2018

"Endocrine therapies are associated with a pattern alopecia similar to androgenetic-type, consistent with the mechanism of action of causal agents," the authors write.

Hyaluronic Acid Filler Feasible for Correcting Infraorbital Hollows

April 09, 2018

The average time to additional treatment was 35.7 days. Adverse effects included bruising, contour irregularities, swelling, and Tyndall effect, and these occurred in 10, 2, 3, and 1% of patients, respectively.

U.S. Providers Fix Complications From Medical Tourism Procedures

April 09, 2018

The researchers found that among 78 identified patients over a 7-year period, complications were seen following abdominoplasty (35 procedures), breast augmentation (25), and foreign body injections (15).

Microneedling + 5-Fluorouracil Effective Vitiligo Treatment

March 23, 2018

The researchers found that overall repigmentation was significantly higher in the patches treated with 5-fluorouracil compared with tacrolimus. Excellent improvement was seen in 48% of the 5-fluorouracil-treated patches versus 16% of tacrolimus-treated patches.

Updated Practice Guideline on Hirsutism Management Issued

March 15, 2018

"Excess facial or body hair is not only distressing to women, it is often a symptom of an underlying medical problem," said Kathryn Martin, MD, Massachusetts General Hospital and lead author of the study.

High Prevalence of Sunburn in U.S. Highlights Need for Targeted Prevention

March 15, 2018

The researchers found that 34.2% of participants experienced sunburn in 2015. The prevalence was higher among younger age groups (51.2% for those aged 18 to 29 years) and in non-Hispanic whites and those with sun-sensitive skin (42.5 and 50.2%, respectively).

Botulinum Toxin Injections After Surgery May Improve Facial Scars

March 09, 2018

The researchers found that, based on the 14 patients who completed the study, the visual analogue scale score and scar width measurements showed a significant improvement in appearance and narrower scars for the halves of the scars treated with botulinum toxin type A (P=0.046 and 0.001, respectively).

How Does Alopecia Impact Health Related Quality of Life?

March 09, 2018

More than half of patients had some association between alopecia and health-related quality of life

First Herbal Supplement and Topical Duo Launched for Skin Conditions

By March 08, 2018

Both Calm topical and Calm + Detox supplements do not contain any steroids, parabens, sulfates, preservatives, petroleum, tree nuts, and gluten.

Therapy Demonstrates Significant Emergence of Hair Regrowth in Alopecia

March 07, 2018

Reduction in dystrophic hair, black and yellow dots, tapered hair for patients with alopecia areata

Early dermatology consultation linked to improved diagnostic accuracy and care in cellulitis

February 28, 2018

Among patients admitted to the hospital for a provisional diagnosis of cellulitis, early dermatologic consultation was associated with improved recognition of pseudo-cellulitis, decreased antibiotic use, and earlier discharge.

Novel Moisturizer Containing Licorice Extract May Improve Erythema Control

February 26, 2018

The researchers found that compared to baseline assessments, both treatments showed a statistically significant improvement based on physician clinical assessment, skin hydration, transepidermal water loss, and patient-assessed visual analog scale following 2 and 4 weeks of treatment.

Rituxan Granted Priority Review for Rare Autoimmune Disease

By February 16, 2018

The disease can be life threatening. Phase 3 study results released last March demonstrated Rituxan substantialy improved pemphigus vulgaris remission rates and successful tapering.

Oral JAK1 Inhibitor Gets Breakthrough Tx Designation for Atopic Dermatitis

By February 15, 2018

In December, a Phase 3, randomized, double-blind, placebo-controlled trial (JADE) was initiated to evaluate the safety and efficacy of PF-04965842 in 375 patients aged ≥12 years with moderate to severe AD.

Efficacy of Omalizumab for Refractory CSU Assessed in Real-World Settings

February 13, 2018

The remaining 3 patients had well-controlled disease after omalizumab treatment. In 30% of patients, the best response to omalizumab was achieved after interval administration of a 9-day course of methylprednisolone (total dose of 188mg)

Topical Nitrates Effective for Treating Raynaud's Phenomenon

By February 09, 2018

A total of 7 trials involving 346 patients were identified; nitroglycerin ointments were used in 4 trials, MQX-503 in 2 trials, and a compounded nitrite in 1 trial.

He Said, She Said: Clinician Sued After Patient Suffers Severe Drug Reaction

By February 07, 2018

It is essential to document warnings, especially significant ones, like this.

Stem Cell Transplant May Be Effective for Systemic Sclerosis

February 07, 2018

The researchers found that, over 7 years of follow-up, there was significant sustained improvement in skin score as well as in vasculopathy and gastrointestinal manifestations.

Tofacitinib + Phototherapy May Be Beneficial for Vitiligo Treatment

February 06, 2018

Case reports describe repigmentation of vitiligo with facial involvement in Hispanic woman, white man

Carboxytherapy vs. Platelet-Rich Plasma for Treating Stretch Marks

January 22, 2018

The fibronectin-stained area from skin biopsies was significantly higher in both groups after treatment compared with before, and it was significantly higher after carboxytherapy compared to PRP.