METOZOLV ODT
Generic Name for METOZOLV ODT
Metoclopramide (as HCl) 5mg, 10mg; orally-disintegrating tabs; mint flavored.
Legal Classification:
Rx
Pharmacological Class for METOZOLV ODT
Prokinetic.
Manufacturer of METOZOLV ODT
Salix Pharmaceuticals, Inc.
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Indications for METOZOLV ODT
Short-term (4–12 weeks) therapy for symptomatic refractory GERD.
Adult dose for METOZOLV ODT
Allow tablet to dissolve on tongue. 10–15mg 4 times daily 30 minutes before meals and at bedtime. Intermittent symptoms: up to 20mg prior to provoking situation; max 12 weeks per therapeutic course. Renal impairment: reduce dose.
Children's dosing for METOZOLV ODT
Not recommended.
Contraindications for METOZOLV ODT
When stimulation of GI motility may be dangerous (eg, obstruction, perforation, or hemorrhage). Pheochromocytoma. Epilepsy. Concomitant drugs which may cause extrapyramidal reactions (eg, antidepressants, antipsychotics, neuroleptics).
Warnings/Precautions for METOZOLV ODT
Discontinue if signs/symptoms of tardive dyskinesia develop; risk increases with duration of treatment and total cumulative dose. Parkinsonism. History of depression. Hypertension. CHF. Arrhythmia. Elderly. Pregnancy (Cat.B). Nursing mothers.
Interactions for METOZOLV ODT
Hypertensive crisis with MAOIs. Additive sedation with alcohol, other CNS depressants. Antagonized by anticholinergics and narcotics. Monitor insulin use; may diminish gastric and accelerate intestinal absorption of drugs or food.
Adverse Reactions for METOZOLV ODT
Headache, nausea, vomiting, fatigue, somnolence, dizziness, extrapyramidal effects, parkinsonism, tardive dyskinesia, neuroleptic malignant syndrome, hypertension.
How is METOZOLV ODT supplied?
Tabs—10 x 10 (blister packs)
Related Disease:
GERD {GERD}