METOZOLV ODT

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Generic Name for METOZOLV ODT

Metoclopramide (as HCl) 5mg, 10mg; orally-disintegrating tabs; mint flavored.

Legal Classification:

Rx

Pharmacological Class for METOZOLV ODT

Prokinetic.

Manufacturer of METOZOLV ODT

Salix Pharmaceuticals, Inc.

Indications for METOZOLV ODT

Short-term (4–12 weeks) therapy for symptomatic refractory GERD.

Adult dose for METOZOLV ODT

Allow tablet to dissolve on tongue. 10–15mg 4 times daily 30 minutes before meals and at bedtime. Intermittent symptoms: up to 20mg prior to provoking situation; max 12 weeks per therapeutic course. Renal impairment: reduce dose.

Children's dosing for METOZOLV ODT

Not recommended.

Contraindications for METOZOLV ODT

When stimulation of GI motility may be dangerous (eg, obstruction, perforation, or hemorrhage). Pheochromocytoma. Epilepsy. Concomitant drugs which may cause extrapyramidal reactions (eg, antidepressants, antipsychotics, neuroleptics).

Precautions for METOZOLV ODT

Discontinue if signs/symptoms of tardive dyskinesia develop; risk increases with duration of treatment and total cumulative dose. Parkinsonism. History of depression. Hypertension. CHF. Arrhythmia. Elderly. Pregnancy (Cat.B). Nursing mothers.

Interactions for METOZOLV ODT

Hypertensive crisis with MAOIs. Additive sedation with alcohol, other CNS depressants. Antagonized by anticholinergics and narcotics. Monitor insulin use; may diminish gastric and accelerate intestinal absorption of drugs or food.

Adverse Reactions for METOZOLV ODT

Headache, nausea, vomiting, fatigue, somnolence, dizziness, extrapyramidal effects, parkinsonism, tardive dyskinesia, neuroleptic malignant syndrome, hypertension.

How is METOZOLV ODT supplied?

Tabs—10 x 10 (blister packs)

Related Disease:

GERD {GERD}

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