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METHYLIN CHEWABLE
ADHD
Sleep-wake disorders
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Drug Name:

METHYLIN CHEWABLE CII

Generic Name and Formulations:
Methylphenidate HCl 2.5mg, 5mg, 10mg; chew tabs; grape flavor; contains phenylalanine.

Company:
Shionogi, Inc.

Therapeutic Use:

Indications for METHYLIN CHEWABLE:

Attention deficit hyperactivity disorder.

Adult:

10–60mg daily in 2–3 divided doses preferably 30–45 mins before meals. Chew tabs: take with 8oz of water or other fluid.

Children:

<6yrs: not recommended. ≥6yrs: initially 5mg twice a day before breakfast and lunch. Increase gradually by 5–10mg per week if needed; max 60mg daily.

See Also:

METHYLIN ORAL SOLUTION

Methylphenidate Extended-Release

Methylphenidate

Contraindications:

During or within 14 days of MAOIs. Marked anxiety, tension, agitation. Glaucoma. History of tics or Tourette's syndrome in patient or family.

Warnings/Precautions:

Abuse potential. Emotionally unstable (eg, drug or alcohol abusers). Avoid in known structural cardiac abnormalities, cardiomyopathy, serious arrhythmias, coronary artery disease, and other cardiac problems. Hypertension. Heart failure. Recent MI. Arrhythmia. Assess cardiovascular status prior to initiation. Psychosis. Bipolar disorder. Depression. Monitor for worsening of aggressive behavior or hostility. Seizure disorder: discontinue if occur. Risk of peripheral vasculopathy, including Raynaud's phenomenon; monitor for digital changes. Reduce dose or discontinue if paradoxical aggravation occurs. Reevaluate periodically. Monitor growth (esp. children), BP, HR, CBC, differential, and platelet counts. Pregnancy or women of childbearing potential: not recommended.

Interactions:

See Contraindications. Caution with pressor agents, anticonvulsants. May increase levels of anticonvulsants, oral anticoagulants, tricyclics, phenylbutazone. Antagonizes guanethidine, other antihypertensives.

Adverse Reactions:

Insomnia, nervousness, CNS overstimulation, anorexia, weight loss, abdominal pain, nausea, dizziness, headache, dyskinesias, hypertension, tachycardia, blood dyscrasias, rash; visual disturbances, arrhythmias, Tourette's syndrome, toxic psychosis, seizures, priapism.

How Supplied:

Tabs, ext-rel tabs—contact supplier; Chew tabs—100; Oral soln—500mL

Indications for METHYLIN CHEWABLE:

Narcolepsy.

Adult:

10–60mg daily in 2–3 divided doses preferably 30–45 mins before meals. Chew tabs: take with 8oz of water or other fluid.

Children:

<6yrs: not recommended. ≥6yrs: initially 5mg twice a day before breakfast and lunch. Increase gradually by 5–10mg per week if needed; max 60mg daily.

See Also:

METHYLIN ORAL SOLUTION

Methylphenidate Extended-Release

Methylphenidate

Contraindications:

During or within 14 days of MAOIs. Marked anxiety, tension, agitation. Glaucoma. History of tics or Tourette's syndrome in patient or family.

Warnings/Precautions:

Abuse potential. Emotionally unstable (eg, drug or alcohol abusers). Avoid in known structural cardiac abnormalities, cardiomyopathy, serious arrhythmias, coronary artery disease, and other cardiac problems. Hypertension. Heart failure. Recent MI. Arrhythmia. Assess cardiovascular status prior to initiation. Psychosis. Bipolar disorder. Depression. Monitor for worsening of aggressive behavior or hostility. Seizure disorder: discontinue if occur. Risk of peripheral vasculopathy, including Raynaud's phenomenon; monitor for digital changes. Reduce dose or discontinue if paradoxical aggravation occurs. Reevaluate periodically. Monitor growth (esp. children), BP, HR, CBC, differential, and platelet counts. Pregnancy or women of childbearing potential: not recommended.

Interactions:

See Contraindications. Caution with pressor agents, anticonvulsants. May increase levels of anticonvulsants, oral anticoagulants, tricyclics, phenylbutazone. Antagonizes guanethidine, other antihypertensives.

Adverse Reactions:

Insomnia, nervousness, CNS overstimulation, anorexia, weight loss, abdominal pain, nausea, dizziness, headache, dyskinesias, hypertension, tachycardia, blood dyscrasias, rash; visual disturbances, arrhythmias, Tourette's syndrome, toxic psychosis, seizures, priapism.

How Supplied:

Tabs, ext-rel tabs—contact supplier; Chew tabs—100; Oral soln—500mL

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