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MENVEO

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MENVEO (meningococcal [Groups A, C, Y, W-135] oligosaccharide diphtheria CRM197 conjugate vaccine)

Generic Name for MENVEO

Neisseria meningitidis oligosaccharide conjugate vaccine (Corynebacterium diphtheriae CRM197 protein); 10mcg of Group A + 5mcg each of Group C, Y, and W-135 + 32.7–64.1mcg of diphtheria CRM197 protein; per 0.5mL; lyophilized pwd for IM inj after reconstitution; preservative-free.

Legal Classification:

Rx

Manufacturer of MENVEO

Novartis Pharmaceuticals Corp

Indications for MENVEO

Meningitis immunization.

Adults and Children:

<2yrs: not recommended. Give by IM inj only in deltoid muscle. 2–55yrs: 0.5mL once. Monitor 15min post-dose. For children 2–5yrs: if continued high risk, may give 2nd dose 2mos after the 1st dose.

Contraindications for MENVEO

Life-threatening reaction to any previous CRM197 or other diphtheria toxoid or meningococcal-containing vaccine.

Warnings/Precautions for MENVEO

Immunodeficiency. Bleeding disorders (eg, hemophilia, thrombocytopenia, during anticoagulant therapy). Have epinephrine inj (1:1000) available. Possible risk of Guillain-Barre Syndrome. Labor & delivery. Pregnancy (Cat.B). Nursing mothers.

Interactions for MENVEO

Immunosuppressants (eg, irradiation, antimetabolites, alkylating agents, cytotoxic drugs, high-dose steroids) may get suboptimal response. Concomitant vaccines: see literature.

Adverse Reactions for MENVEO

Inj site pain, erythema, induration; irritability, headache, malaise, nausea, myalgia, arthralgia; syncope (transient tonic-clonic movements, other seizure-like activity possible post-dose).

How is MENVEO supplied?

Vials—5 doses (1 vial of lyophilized MenA conjugate component + 1 vial of liquid MenCYW-135 conjugate component)

Related Disease:

Immunization

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