Warfarin-Associated ICH in Stroke Patients: High or Low Risk?
the MPR take:
For patients with ischemic stroke taking warfarin, the risk of intracerebral hemorrhage (ICH) is low and remained unchanged over an 8-year span. This study, published in the journal Stroke, evaluated 6,039 patients with ischemic stroke discharged on warfarin over two four-year periods and found that the risk of ICH ranged from 0.37% in the first period to 0.39% in the second period (adjusted hazard ratio, 1.04; 95% confidence interval, 0.73–1.48). While ICH has been connected to oral anticoagulants, in stroke patients taking warfarin this risk was low.
Background and Purpose- The aim was to investigate the risk of intracerebral hemorrhage (ICH) in patients with ischemic stroke taking warfarin and whether this risk changed over time. The patients was studied in two 4-year periods (inclusion 2001-2004: follow-up until 2005 and inclusion 2005–2008: follow-up until 2009) for which rates of subsequent ICH were calculated.
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