Vitamin D, Asthma Exacerbations: Is There a Connection?
the MPR take:
While a new study has found no significant association between serum 25OHD (vitamin D) levels and physician-diagnosed asthma, a strong association was seen between vitamin D levels and asthma exacerbations. Data reviewed on a cohort of adults aged 22–50 with documented vitamin D status between July 1, 2008 and July 1, 2012 found similar vitamin D levels across patients diagnosed with asthma and the general population. Patients with a vitamin D deficiency and asthma, however, had a 25% greater risk of exacerbation (defined as an oral corticosteroid prescription, >5 prescriptions for short-acting beta agonists, or >4 visits to a physician for asthma during the study time frame) vs. patients with normal vitamin D levels. Although the role of vitamin D and respiratory diseases remains unclear, patients with asthma and low serum levels could be at a greater risk of exacerbations associated with asthma.
A cohort of Israeli adults aged 22–50 years with documented vitamin D status were extracted from Clalit Health Services (HMO) between July 1, 2008 and July 1, 2012. Among this population those with physician diagnosed asthma and asthma exacerbations were identified.
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