Vascular Closure Devices Reduce Complications From PCI

Vascular Closure Devices Reduce Complications From PCI
Vascular Closure Devices Reduce Complications From PCI

(HealthDay News) – Vascular closure devices (VCDs) are associated with a significant reduction in vascular complications and need for transfusion in patients having transfemoral percutaneous coronary intervention (PCI), according to a study published in the Nov. 19 issue of the Annals of Internal Medicine.

Hitinder S. Gurm, MD, from the University of Michigan in Ann Arbor, and colleagues analyzed outcomes in consecutive patients having emergent and non-emergent PCI from 2007–2009, treated in 32 Michigan hospitals participating in a large multicenter quality improvement collaborative.

The researchers found that, of the 85,048 PCIs performed during the study, 37% of procedures used VCDs. VCDs were associated with reductions in vascular complications (odds ratio [OR], 0.78; P=0.001) and post-procedure transfusions (OR, 0.85; P=0.011) in propensity-matched analysis. Except for patients with a body mass index (BMI) <25kg/m² and those treated with platelet glycoprotein (GP) IIb/IIIa inhibitors, the findings were consistent. More specifically, VCDs were associated with fewer hematomas (OR, 0.69; P<0.001) or pseudoaneurysms (OR, 0.54; P<0.001) and an increase in the odds of retroperitoneal bleeding (OR, 1.57; P=0.009).

"VCDs were associated with a significant reduction in vascular complications and need for transfusion in this large cohort of patients having transfemoral PCI," the authors write.

Blue Cross Blue Shield of Michigan partially funded the study.

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