U.S. Children With Cystic Fibrosis Are Living Longer

U.S. Children With Cystic Fibrosis Are Living Longer
U.S. Children With Cystic Fibrosis Are Living Longer

(HealthDay News) — In the United States, children born in 2010 with cystic fibrosis (CF) are projected to live longer than those born earlier, according to a study published in the August 19 issue of the Annals of Internal Medicine.

In a registry-based study, Todd MacKenzie, PhD, from the Dartmouth-Hitchcock Medical Center in Lebanon, NH, and colleagues characterized trends in CF survival from 2000–2010 and projected survival for children born with CF in 2010. Data were collected for all patients represented in the Cystic Fibrosis Foundation Patient Registry (CFFPR) between 2000–2010.

The researchers observed an increase in the number of patients in the CFFPR, from 21,000 in 2000 to 26,000 in 2010, and their median age increased from 14.3 to 16.7 years. Per year, the adjusted mortality decreased 1.8%, and males had a 19% lower adjusted mortality risk. If mortality remains at 2010 levels, the median survival per child born and diagnosed with CF in 2010 is projected to be 37 and 40 years for females and males, respectively. If mortality continues to decrease at rates seen between 2000–2010, survival is projected to be >50 years.

"Children born and diagnosed with CF in the United States in 2010 are expected to live longer than those born earlier," the authors write. "This has important implications for prognostic discussions and suggests that the health care system should anticipate greater numbers of adults with CF."

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