Topical Antifungal Treatments for Tinea Infections Reviewed
the MPR take:
What are the most effective treatments for tinea infections? A Cochrane Library review assessed published randomized controlled studies of patients with proven tinea corporis or tinea cruris regarding efficacy of treatment and adverse effects. While many studies found a greater mycological or clinical cure rate in patients treated with terbinafine, naftifine 1%, or clotrimazole 1% vs. placebo, no difference was seen between azoles and benzylamines in mycological cure rate. Compared to azole and steroid combination creams, azoles were slightly less effective in achieving clinical cure immediately at the end of treatment, however no difference was seen in mycological cure rate. All treatments in the review were found to be effective and there was no evidence for a difference in cure rates between tinea cruris and tinea corporis. Physicians should assess factors that could make certain treatments more appealing to patients, such as shorter treatment duration and fewer applications of medicine.
To assess the effects of topical antifungal treatments in tinea cruris and tinea corporis. We also searched five trials registers, and checked the reference lists of included and excluded studies for further references to relevant randomised controlled trials. Mycological and clinical cure were assessed in the majority of studies, along with adverse effects.
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