Threshold for Prompt, Aggressive BP Tx Identified
(HealthDay News) — Patients with systolic blood pressure >150mmHg face increased risks without aggressive drug treatment started within a month and a half, according to research findings published February 5 in The BMJ.
Alexander Turchin, MD, director of informatics research in the division of endocrinology at Brigham and Women's Hospital in Boston, and colleagues examined the medical records of 88,756 British patients with hypertension to pinpoint the precise blood pressure level and critical time points at which treatment was tied to a decrease in the risk of hypertension-related death.
In patients with systolic blood pressures between 130–150mmHg, the research team did not detect an increase in risk, but above the 150 threshold, the team observed progressively greater risk. The study authors also discovered that delaying the intensification of treatment by more than 1.4 months after a blood pressure rise past 150mmHg increased a person's risk of heart attack, stroke or early death. In addition, the research team behind the new study found that when patients received a reassessment of blood pressure levels more than 2.7 months after doctors stepped up treatment, their risk of early death also increased.
"There have been many studies that have looked at what the blood pressure threshold should be," Turchin told HealthDay. "Where the American guidelines are currently silent is how quickly we need to respond, and they are silent because there are no data in that area."