The Use of Lidodaine Medicated Plasters in Trigeminal Neuralgia
the MPR take:
For patients who do not tolerate or refuse to use other therapies to treat their trigeminal neuralgia (TN), lidocaine medicated plaster (LMP) may be an effective treatment option, says a new study published in the journal The Annals of Pharmacotherapy. Two patients with classic TN who could not tolerate conventional TN treatment were given 5% LMP to treat the painful attacks caused by their condition. The use of LMP resulted in a reduction in the number of pain paroxysms and pain intensity leading researchers to conclude that LMP may be a viable option for those patients that are left without any alternatives. Researchers believe that the effects of LPM may last beyond the drug's pharmacokinetics, decreasing the way pain is amplified in the central nervous system.
Trigeminal neuralgia (TN) is a neuropathic pain condition affecting one or more branches of the trigeminal nerve. It is characterized by unilateral, sudden, shock-like, and brief painful attacks, which follow the distribution of trigeminal nerve branches, and with no other accompanying sensorimotor or autonomic signs and symptoms.