Stem Cell Therapy for Heart Disease Questioned
the MPR take:
Two newly published reviews are raising doubts about the effectiveness of stem cell therapy in treating heart disease. The first one, published in BMJ, located over 600 discrepancies in 133 reports from 49 separate clinical trials of autologous bone marrow stem cells to treat heart disease. The authors also found that as the number of errors increased in a study, so too did the likelihood of a reported large treatment effect. In the second study, a Cochrane review found that stem cells could have some benefit for heart disease therapy but studies with a greater number of participants are needed to confirm.
For more than a decade cardiac stem cell therapy has attracted an enormous amount of attention, promise, and research dollars. Now an original and important new study published in BMJ finds that many of the most promising results in the field are illusory and that the potential benefits of stem ...
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