Statins May Speed Wound Healing Post-Surgery
the MPR take:
A retrospective study in the Annals of Thoracic Surgery points to statins as possibly having a positive benefit in surgical wound healing. In the review of 20 studies on statins and surgical wound healing, statin use led to a 30% faster rate of wound epithelialization and an 80% greater wound-breaking strength with faster wound healing rates (13.0 days vs. 18.7 days, P<0.0001). While one of the two studies involving humans found no benefit for patients undergoing hernia surgery, it did not account for the use of other blood-thinning medications that could have impacted the results. It is believed that statins reduce the activity of white cell production without impacting its function in the healing process.
Statins, the widely used cholesterol-lowering drugs, may have a role in surgical wound healing, a new analysis suggests. They demonstrated various mechanisms by which statins can lower inflammation, improve the mechanical strength of a healing wound, promote the growth of blood vessels and reduce healing time. Most were animal or laboratory tissue studies, but two were studies in humans.
READ FULL ARTICLE From The New York Times