Sildenafil Use May Increase Melanoma Risk
the MPR take:
Research published in the journal JAMA Internal Medicine points to an association between sildenafil use and an increase in melanoma risk. In this prospective cohort study, men were interviewed about their use of sildenafil for erectile dysfunction and about their overall skin health. Of the 25,848 men that were analyzed, 142 melanoma, 580 squamous cell carcinoma, and 3030 basal cell carcinoma cases were identified. While no significant increase was seen in squamous cell carcinoma or basal cell carcinoma risk, both recent and ever use of sildenafil was associated with an increased risk of developing melanoma. Researchers state that while the study was not sufficient enough to change recommendations on sildenafil use, more research into this association needs to be done.
The study, published in JAMA Internal Medicine, found sildenafil, commonly known as Viagra, may increase a man's risk for melanoma by as much as 84 percent. They then tracked occurrences of various types of skin cancer -- melanoma, squamous cell carcinoma and basal cell carcinoma -- based on self-reported questionnaires over the next 10 years.
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