Response to Resistance Exercise Depends on a Person's Genetic Risk for Obesity

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Resistance Training Effects Vary Per Genetic Profiles
Resistance Training Effects Vary Per Genetic Profiles

(HealthDay News) — Resistance training seems to be most effective for people with a low genetic risk for a high body mass index, according to a study published online April 30 in the International Journal of Obesity.

Researchers examined genetic markers of 148 women. They were between 30 and 65 years old. All participated in the year-long Bone Estrogen and Strength Training study. Each woman received a genetic risk score for obesity, which was based on 21 genetic markers believed to affect body weight.

Eighty-four women were asked to participate in supervised, high-intensity resistance training and moderate weight-bearing exercises. The exercise sessions lasted for 75 minutes each. The women were asked to do these exercises three days a week for one year. During this time, the women took calcium supplements but made no other changes to their typical diet. The participants recorded their food intake at random intervals.

The researchers found that the benefits of resistance training, which included weight loss as well as loss of body fat and abdominal fat, depended on a woman's genetics and her risk for obesity. More research is needed, the study authors pointed out. They said that future studies should include a more diverse group of people. And they added that future studies should also identify ideal weight-management strategies based on an individual's genetic profile.

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