Rapid Weight Loss May Not Mean a Quicker Regain

the MPR take:

Current dietary guidelines recommend gradual vs. rapid weight loss to treat obesity, indicating rapid weight loss is more quickly regained. However, a recent 2-phase intervention study in a Melbourne metropolitan hospital found that the rate of weight loss did not impact the proportion of weight regained within 144 weeks. Study participants with a BMI between 30–45kg/m2 were randomized to the gradual weight loss (n=103) or rapid weight loss (n=97) program between August 8, 2008–March 9, 2010. After Phase 1, 50% of the gradual weight loss group and 81% of the rapid weight loss group achieved ≥12.5% weight loss and entered Phase 2. At the end of Phase 2, both groups showed similar results in regaining most of their lost weight (gradual weight loss 76.3% regain, 95% CI 65.2–87.4 vs. rapid weight loss 70.5% regain, 95% CI 65.8–86.8). Study data were not consistent with the widely held notion that weight lost rapidly is more quickly regained. 

The effect of rate of weight loss on long-term weight management: a randomised controlled trial
The effect of rate of weight loss on long-term weight management: a randomised controlled trial
The effect of rate of weight loss on long-term weight management: a randomised controlled trial. By - Katrina Purcell BSc, Priya Sumithran PhD, Luke A Prendergast PhD, Celestine J Bouniu MBBS, Eliz...

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