Ovarian Conservation Safe in Endometrial Cancer, but Use Low
(HealthDay News) — Despite the safety of ovarian conservation, the majority of young women with endometrial cancer still undergo oophorectomy, according to a study published in the January issue of Obstetrics & Gynecology.
Jason D. Wright, MD, from Columbia University in New York City, and colleagues utilized data from the National Cancer Database (1998 to 2012) to identify 15 648 women (<50 years of age) with stage I endometrioid adenocarcinoma of the endometrium who underwent hysterectomy. Women were characterized based on whether they underwent oophorectomy (92.8%) or had ovarian conservation (7.2%).
The researchers found that the rate of ovarian conservation was relatively stable (6.9% in 1998 versus 7.1% in 2012; P = 0.91). Younger women, black women, those with low-grade and earlier stage tumors, and women treated at community hospitals more commonly had ovarian conservation. Ovarian conservation was not independently associated with survival (hazard ratio, 0.94; 95% confidence interval, 0.65 to 1.37).
"Ovarian conservation does not adversely affect survival for women with early-stage endometrial cancer," the authors write.