Osteoporosis/Osteopenia Prevalent in Chronic Pancreatitis
(HealthDay News) — Sixty-five percent of patients with chronic pancreatitis have osteoporosis or osteopenia, according to a meta-analysis published in the February issue of Clinical Gastroenterology and Hepatology.
Sinead N. Duggan, PhD, of Trinity College Dublin, and colleagues performed a systematic review of the literature and meta-analysis to assess the prevalence of osteoporosis and osteopenia in patients with chronic pancreatitis.
The researchers found that 10 studies, involving a total of 513 patients, were eligible for inclusion. The pooled prevalence rate in patients with chronic pancreatitis was 23.4% (95% confidence interval [CI], 16.6–32.0) for osteoporosis and 39.8% for osteopenia (95% CI, 29.1–51.6). Among patients with chronic pancreatitis, the pooled prevalence rate for either osteoporosis or osteopenia was 65% (95% CI, 54.7–74.0).
"We recommend that bone-health assessment should form an integral part of the medical/nutritional work-up of patients with chronic pancreatitis to prevent and treat osteoporosis and, ultimately, to prevent fracture and its associated morbidity," the authors write.