Obesity, Dementia Risk Varies with Age

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Obesity, Dementia Risk Varies with Age
Obesity, Dementia Risk Varies with Age

(HealthDay News) — The association between obesity and subsequent dementia varies with the age at which obesity is first recorded, according to a study published online August 20 in the Postgraduate Medical Journal.

Clare J. Wotton and Michael J. Goldacre, BM, BCh, from the University of Oxford in the United Kingdom, and colleagues utilized national administrative statistical data on hospital care and mortality in England (1999–2011) to identify 451,232 people with obesity and a cohort of controls.

The researchers found that the risk for dementia in people admitted to the hospital with obesity at 30–39 years of age was significantly increased (risk ratio [RR], 3.5). Increasing age at obesity gradually reduced the risk for dementia, from 1.7 in people aged 40–49 years when obesity was first recorded to 1.4 in those whose obesity was first recorded at 60–69 years. There was neither an increased nor a reduced risk of subsequent dementia for people whose obesity was first recorded in their 70s (RR, 0.97; 95% confidence interval, 0.93–1.01), while those aged ≥80 years had a reduced risk of subsequent dementia (RR, 0.78; 95% confidence interval, 0.74–0.82).

"While obesity at a younger age is associated with an increased risk of future dementia, obesity in people who have lived to about 60–80 years of age seems to be associated with a reduced risk," the authors write.

Abstract
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