Melanoma's Sugar Dependence Blocked

the MPR take:

With approximately 40% of melanomas caused by BRAF gene mutations and dependent on glucose for cancer cell growth, researchers have discovered a way to control tumor growth with specific drug therapy. Tiffany Parmenter and colleagues at the Peter MacCallum Cancer Centre in Australia saw that by reducing the high use of glucose by the tumors, they were able to halt the growth of the tumors anywhere from a few weeks to a few years. The tumors became resistant to the drug effects after the growth restarted and the glucose supply was replenished. The team hopes to develop new treatments to kill the remaining cancer cells by blocking the genes in charge of use and regulation of glucose. 

Melanoma's Sugar Dependence Blocked
Melanoma's Sugar Dependence Blocked
Melanoma cells are dependent on glucose to grow and spread, Melbourne researchers have found, paving the way for therapies that can halt cancer growth by blocking its fuel source. "While we know these drugs are incredibly effective in patients who have this particular mutation, it will only stop ...

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