Low Vitamin D Could Spell Trouble for Patients with IBD
the MPR take:
Patients with inflammatory bowel diseases (IBD) typically have a deficiency of vitamin D; however, what effect this deficiency has on the patient besides a reduction in bone health has not been fully elucidated. In a study published in the journal Clinical Gastroenterology and Hepatology, an analysis of 2,809 IBD patients showed nearly 1/3 had a vitamin D deficiency. Of this group, 7% (196 patients) went on to develop cancer (median follow-up period of 11yrs), particularly colorectal cancer. Researchers concluded that patients with IBD and vitamin D deficiency were at an increased risk of developing cancer compared to IBD patients with normal vitamin D levels. An 8% risk reduction for colorectal cancer was noted with each 1ng/mL increase of plasma vitamin D.
Vitamin D deficiency is common among patients with IBD (Crohn's disease or ulcerative colitis). The effects of low plasma 25-hydroxy vitamin D (25[OH]D) on outcomes other than bone health are understudied in patients with IBD. They report in Clinical Gastroenterology and Hepatology that, in a ...
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