Liver Disease Ups CKD Risk in Type 1 Diabetes
the MPR take:
A study published in Diabetes Care revealed for the first time that nonalcoholic fatty liver disease (NAFLD) is strongly associated with an increased incidence of chronic kidney disease (CKD) in patients with type 1 diabetes. 261 type 1 diabetic adults with preserved kidney function and with no macroalbuminuria were assessed over a period of 5.2 years, with NAFLD being associated with an increased risk of incident CKD. This risk persisted even after adjustments for age, sex, duration of diabetes, hypertension, A1C, and baseline estimated glomerular filtration rate (eGFR). The authors state that NAFLD measurement can improve CKD risk prediction outside of traditional cardio-renal risk factors.
OBJECTIVE: There is no information about the role of nonalcoholic fatty liver disease (NAFLD) in predicting the development of chronic kidney disease (CKD) in type 1 diabetes. RESEARCH DESIGN AND METHODS: We studied 261 type 1 diabetic adults with preserved kidney function and with no ...
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