Is Miralax + Gatorade a Good Choice for Bowel Prep Before Colonoscopy?

the MPR take:

A new study published in The American Journal of Gastroenterology investigates the use of Miralax (polyethylene glycol 3350; Merck) and Gatorade for use as a bowel preparation before colonoscopy. While polyethylene glycol (PEG) is considered a popular bowel cleanser prior to colonoscopy, large volume PEG preparations could potentially reduce patient compliance.  A search of multiple databases produced five studies where Miralax/Gatorade (M/G), a lower volume and more palatable preparation, was compared to other PEG preparations before colonoscopy.  Results showed statistically significantly fewer satisfactory bowel preparations associated with M/G compared with PEG; however, patients were willing to repeat M/G more so than PEG. In terms of polyp detection, no statistically significant differences were seen between the two bowel preparations. Based on this data, researchers conclude that for bowel preparation prior to colonoscopy, PEG appears to be superior to M/G.

OBJECTIVES: Polyethylene glycol (PEG) is a very popular bowel preparation for colonoscopy. However, its large volume may reduce patient compliance, resulting in suboptimal preparation. Recently, a combination of Miralax and Gatorade has been studied in various randomized controlled trials (RCTs) as a lower volume and more palatable bowel preparation.


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