In Genitourinary Cancers, Suicide is a Public Health Concern

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In Genitourinary Cancers, Suicide is a Public Health Concern
In Genitourinary Cancers, Suicide is a Public Health Concern

(HealthDay News) — Suicide is a public health concern for patients with genitourinary cancer, especially bladder cancer, according to a study published online February 17 in Cancer.

Zachary Klaassen, MD, from the Medical College of Georgia-Georgia Regents University in Augusta, and colleagues characterized suicide rates among patients with prostate, bladder, kidney, testis, and penile cancer identified from the Surveillance, Epidemiology, and End Results database (1988 to 2010).

The researchers identified 2,268 suicides among 1,239,522 individuals with genitourinary malignancies. For patients with cancer, the standardized mortality ratios were 1.37 (95% confidence interval [CI], 0.99–1.86) for prostate cancer, 2.71 (95% CI, 2.02–3.62) for bladder cancer, 1.86 (95% CI, 1.32–2.62) for kidney cancer, 1.23 (95% CI, 0.88–1.73) for testis cancer, and 0.95 (95% CI, 0.65–1.35) for penile cancer. Male gender correlated with odds of suicide in patients with bladder and kidney cancer (odds ratios, 6.63 and 4.98, respectively). For patients with prostate, bladder, and testis cancer, increasing age correlated with odds of suicide (odds ratio range, 1.03–1.06). In patients with prostate, bladder, and kidney cancer, distant disease correlated with suicide (odds ratio range, 2.82–5.43). Among those with prostate, bladder, and kidney cancer, suicide was less likely for African-American vs. white patients (odds ratio range, 0.26–0.46).

"Suicide in patients with genitourinary malignancies poses a public health dilemma, especially among men, the elderly, and those with aggressive disease," the authors write. "Clinicians should be aware of risk factors for suicide in these patients."

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