HIV-Infected Women May Benefit from HPV Vaccine

the MPR take:

A study published in the journal Clinical Infectious Diseases shows that the quadrivalent HPV vaccine is safe and effective in women infected with HIV. Because of increased immunosuppression, a disproportionate amount of HIV-infected women are affected with HPV-related diseases. In this study, the safety and efficacy of administering a quadrivalent HPV vaccine was evaluated in three groups based on CD4 count. For HPV types 6, 11, 16, and 18, patients with CD4>350 cells/mm3 had seroconversion proportions at 28 weeks of 96%, 98%, 99%, and 91%, respectively. Patients with CD4<200 cells/mm3 had lower seroconversion. No safety issues were noted in patients participating in the study. The administration of HPV vaccine can be beneficial to HIV-infected women since the vaccine has been shown to prevent cancers such as cervical and anal cancers, cancers which may grow faster in women whose immune systems are already suppressed.

HIV-Infected Women May Benefit from HPV Vaccine
HIV-Infected Women May Benefit from HPV Vaccine
Vaccines against cervical cancer work well even in sexually active women with H.I.V., a new study has found. The new study, done on 319 women in Brazil, South Africa and the United States and published by Clinical Infectious Diseases, found that most could make antibodies to the four strains of ...

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