HIV-Infected Men at Risk for Heart Disease

the MPR take:

HIV-infected men are more likely to have coronary artery plaque than HIV-uninfected men, independent of cardiovascular disease risk factors. In a study published in the Annals of Internal Medicine, participants in the Multicenter AIDS Cohort Study (MACS) were evaluated for presence and extent of coronary artery calcium (CAC) on noncontrast cardiac computed tomography (CT) and of any plaque; noncalcified, mixed, or calcified plaque; or stenosis on coronary CT angiography. Compared to uninfected men, HIV-infected men had a greater prevalence of CAC and any plaque, including noncalcified and mixed, after adjustment for age, race, CT scanning center, and cohort. Additional research is needed to determine if coronary artery plaque is less likely to harden over time in HIV-infected men or if they develop greater amounts of soft plaque. 

HIV-Infected Men at Risk for Heart Disease
HIV-Infected Men at Risk for Heart Disease
Objective:To determine whether HIV-infected men have more coronary atherosclerosis than uninfected men. Participants:HIV-infected (n = 618) and uninfected (n = 383) men who have sex with men who were aged 40 to 70 years, weighed less than 136 kg (200 lb), and had no history of coronary ...

READ FULL ARTICLE From annals.org

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