Higher Antidepressant Doses in Young People Could Up Self-Harm Risk

the MPR take:

A new study in JAMA Internal Medicine has found that young patients who begin antidepressant therapy at a higher-than-recommended dose have an increased risk of self-harm compared to those who started at lower doses. Data from 162,000 patients ages 10–64 revealed that almost 18% of patients began treatment on doses higher than recommended for these medications. Patients <24 years of age had rates of self-harm twice that of those in the same age group taking lower doses. Initiating pharmacotherapy at lower recommended doses and monitoring young patients as they begin antidepressant treatment is encouraged.

Higher Antidepressant Doses in Young People Could Up Self-Harm Risk
Higher Antidepressant Doses in Young People Could Up Self-Harm Risk

Younger patients starting off with a higher-than-recommended dose elevated their risk of self-harm compared with those who started at lower doses, according to a study from the JAMA Internal Medicine based on 162,000 patients ages 10 to 64. Nearly 18% of patients in the study started on doses ...

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