Heart Failure Risk Up During IBD Flares
the MPR take:
Patients with inflammatory bowel disease (IBD) may be at an increased risk of adverse cardiovascular events, and new research shows that the risk is particularly elevated when it comes to heart failure (HF) and active IBD. A new study in the journal Circulation: Heart Failure assessed 23,681 patients with diagnosed IBD for disease activity and hospitalization for HF over an average of 6.4 years. Patients with IBD had a 37% increase risk of hospitalization for HF vs. the control population, with a significantly increased risk during flares (IRR 2.54, 95% CI 2.13–3.04) and persistent activity (IRR 2.73, 95% CI 2.25–3.33]), but not in IBD remission (IRR 1.04, 95% CI 0.94–1.16). The mechanisms underlying this increased risk are unknown, but IBD patients are advised to discuss all cardiovascular risk factors with their physician.
Background: Inflammatory bowel disease (IBD) has been linked to adverse cardiovascular events, but a relation to heart failure is uncertain. Methods and Results: A total of 5,436,647 Danish citizens, with no history of IBD or heart failure, were included on 1 January 1997 and followed until first hospitalization for heart failure, death, or 31 December 2011.
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