For Recurrent Pericarditis, Colchicine May Be Safe, Effective
the MPR take:
A new study has found that colchicine therapy can be considered a safe and effective option for primary and secondary prevention of pericarditis. A review of four prospective randomized studies found that patients with acute and recurring pericarditis taking colchicine has lower rates of recurrent disease and symptom persistence vs. non-colchicine patients. A separate meta-analysis of five additional studies also showed a reduced risk of pericarditis with colchicine use, adding to the cumulative evidence of its safety and efficacy in treating pericarditis. Colchicine is an anti-inflammatory agent used for prophylaxis, treatment of acute gout flares, and familial Mediterranean fever (FMF).
Purpose: A review of published data on the safety and efficacy of colchicine therapy for primary and secondary prevention of pericarditis is presented. Summary Colchicine has been used effectively as an antiinflammatory agent for gout and has shown promise as a treatment for acute and recurrent pericarditis.
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