For Living Donors, Liver Transplant Mortality Rate at 0.2%
(HealthDay News) – The donor mortality rate during living donor liver transplantation (LDLT) is 0.2%, regardless of program experience, according to a study published in the May issue of Liver Transplantation.
Yee Lee Cheah, MD, from Tufts Medical School in Burlington, Mass., and colleagues conducted a worldwide survey of 148 programs performing LDLT to determine the incidence of morbidity and mortality after LDLT as well as the incidence of aborted hepatectomies (AH) and potentially life-threatening near-miss events (during which a donor's life may be in danger but after which there are no long-term sequelae). Surveys were completed by 71 programs (48%) that performed donor hepatectomy 11,553 times and represented 21 countries.
The researchers found the donor mortality rate to be 0.2% (23/11,553), with the majority of deaths occurring within 60 days and all but four deaths related to the donation surgery. Near-miss events and AH occurred with an incidence of 1.1% and 1.2%, respectively. The incidence of donor morbidity or mortality was not affected by program experience; however, near-miss events and AH were more likely in low-volume programs (≤50 LDLT procedures).
"In conclusion, it appears that independently of program experience, there is a consistent donor mortality rate of 0.2% associated with LDLT donor procedures, yet increased experience is associated with lower rates of AH and near-miss events," the authors write.