Evaluating Idiopathic Membranous Nephropathy with Novel ELISA

the MPR take:

In a study published in the American Journal of Clinical Pathology, a novel ELISA (enzyme-linked immunosorbent assay) was able to effectively differentiate between idiopathic and secondary membranous nephropathy. Serum samples were tested for the presence of anti-PLA2R1 using indirect immunofluorescence, Western blotting test, and ELISA.  Both the Western blotting test and indirect immunofluorescence shared high agreement with ELISA.

Older Individuals Have Atypical Stone Presentation
Evaluating Idiopathic Membranous Nephropathy with Novel ELISA

Objectives: Autoantibodies against the M-type phospholipase A2 receptor 1 (anti-PLA2R1) have been demonstrated to be very specific for idiopathic membranous nephropathy (MN). We studied a novel enzyme-linked immunosorbent assay (ELISA) and compared results with results obtained using an indirect ...

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