Epilepsy Drug to Treat Alcoholism?
the MPR take:
A medication to treat seizures may also help reduce the desire to drink for alcoholics, according to newly published results in the American Journal of Drug and Alcohol Abuse. Potiga (ezogabine; GlaxoSmithKline) is indicated as an adjunctive treatment for partial-onset seizures in patients ≥18yrs old and was approved by the FDA in 2011. The use of ezogabine to treat alcoholism is off-label and appears to work in this capacity by opening a potassium channel in the brain (Kv7) that controls brain activity in areas thought to regulate the rewarding effects of alcohol. Follow-up research is needed to determine how ezogabine and Kv7 channels interact and to evaluate the full effects of the drug.
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